офиоболин С

19022-51-6

CAS №: 19022-51-6

Химическое название:: офиоболин С

английское имя:: ophiobolin C

Синонимы:: Zizanin A;ophiobolin C;3-Hydroxy-5-oxoophiobola-7,19-dien-25-al;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1-hydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aS,7R,9aR,10aS)-

CBNumber:: CB31317681

Формула:: C25H38O3

молекулярный вес:: 386.57

MOL File:: 19022-51-6.mol

атрибут

безопасность

использование

поставщик 28

продукт поиска:

офиоболин С атрибут

температура хранения:	Store at -20°C
растворимость:	DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
форма:	Твердый

Заявления о рисках и безопасности

офиоболин С химические свойства, назначение, производство

Описание

Ophiobolin C is a sesterterpenoid fungal phytoxin produced by many species of the genus Bipolaris. It has been identified as an antagonist of chemokine receptor CCR5 binding (IC₅₀ = 40 μM) to the envelope protein gp120 and to CD4, which is known to mediate HIV-1 viral entry into cells. Ophiobolin C is also reported to be cytotoxic to chronic lymphocytic leukemia cells (LC₅₀ = 8 nM).

Использование

Ophiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris. Ophiobolin C inhibits human CCR5 binding to the envelope protein gp120 and CD4 that mediates HIV-1 entry into cells. Blockade of this binding was considered by scientists at Merck as a potential new mode of action for the treatment of HIV-1 infection.

офиоболин С препаратная продукция и сырье

сырьё

препарат

офиоболин С поставщик

Global( 28)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Aladdin Scientific	+1-+1(833)-552-7181	United States	52925	58
BOC Sciences	16314854226; +16314854226	United States	19741	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32077	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	China	12005	58
TargetMol Chemicals Inc.	4008200310	China	24647	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	China	11974	58
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	China	3656	58
Zhejiang Huida Biotech Co., LTD	0571-0571-89903882 15990081639	China	3705	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	China	11217	58
Lynnchem	86-(0)29-85992781 17792393971	China	4587	58

19022-51-6(офиоболин С)подобный поиск:

Стауроспорин