ДГАТ-3

701232-20-4

CAS №: 701232-20-4

Химическое название:: ДГАТ-3

английское имя:: DGAT-3

Синонимы:: DGAT-3;CS-120;T-863;T 863;trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid;trans-Cyclohexaneacetic-acid,-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl];trans-2-(4-(4-(4-aMino-7,7-diMethyl-7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid;Mino-7,7-diMethyl-2-((1r,4r)-4-(4-(4-a7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid;Cyclohexaneacetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-, trans-;2-((1,4-trans)-4-(4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)- phenyl)cyclohexyl)acetic acid;Diglyceride acyltransferase,inhibit,acyl-CoA:cholesterol acyltransferase,T 863,T-863,T863,Inhibitor,Acyltransferase,mono- acylglycerol acyltransferase,Diacylglycerol acyltransferase

CBNumber:: CB31872285

Формула:: C22H26N4O3

молекулярный вес:: 394.47

MOL File:: 701232-20-4.mol

атрибут

безопасность

использование

поставщик 50

продукт поиска:

ДГАТ-3 атрибут

Температура кипения:	616.6±55.0 °C(Predicted)
плотность:	1.36±0.1 g/cm3(Predicted)
температура хранения:	2-8°C
растворимость:	ДМСО: растворим 15 мг/мл (прозрачный раствор)
пка:	4.72±0.10(Predicted)
форма:	пудра
цвет:	От белого до бежевого
FDA UNII:	OF68Z8HK6V

Заявления о рисках и безопасности

WGK Германия	3

ДГАТ-3 химические свойства, назначение, производство

Использование

T863 has been used as a diglyceride acyltransferase (DGAT1) inhibitor:

to provide the opportunity to precisely control the DGAT inhibition
to treat mouse embryonic fibroblasts (MEFs) to analyse lipid droplet biogenesis
to specifically block neutral?lipid synthesis?and lipid droplet formation in HT-1080 cells
to block lipid droplet (LD) formation

Биохимия/физиол Действия

T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.

ДГАТ-3 препаратная продукция и сырье

сырьё

препарат

ДГАТ-3 поставщик

Global( 50)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Amadis Chemical Company Limited	571-89925085	China	131957	58
Aladdin Scientific	+1-+1(833)-552-7181	United States	57505	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58
TargetMol Chemicals Inc.		United States	38466	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30241	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32072	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49374	58
BOC Sciences	+1-631-485-4226	United States	19553	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32951	60
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	China	12005	58

701232-20-4(ДГАТ-3)подобный поиск:

N,N-Диметиланилин Транс-4-аминоциклогексанол