(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

1523404-29-6

CAS №: 1523404-29-6

английское имя:: (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

Синонимы:: 129208;Vps34-IN-2;Vps34 inhibitor 2;Vps-34-IN-2,Vps34 IN 2,Vps34IN2;(S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyri;(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one;(S)-9-(3-Methyl-2-oxobutyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one;(8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one;4H-Pyrimido[1,2-a]pyrimidin-4-one, 6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-, (8S)-

CBNumber:: CB42742380

Формула:: C18H25F3N4O3

молекулярный вес:: 402.41

MOL File:: 1523404-29-6.mol

атрибут

безопасность

использование

поставщик 14

продукт поиска:

(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one атрибут

Температура кипения:	466.4±55.0 °C(Predicted)
плотность:	1.40±0.1 g/cm3(Predicted)
температура хранения:	Sealed in dry,Room Temperature
растворимость:	Ethanol: 50 mg/mL (124.25 mM)
пка:	0.08±0.40(Predicted)
форма:	Solid
цвет:	White to off-white

Заявления о рисках и безопасности

(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one химические свойства, назначение, производство

Использование

(8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one, is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively.

(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one препаратная продукция и сырье

сырьё

(S)-8-chloro-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one 2-Амино-4-(трифторметил) пиримидин (S)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one 1-бром-3-метил-2-бутанон

препарат

(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one поставщик

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TargetMol Chemicals Inc.	+8613564774135	United States	19881	58
TargetMol Chemicals Inc.		United States	38631	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32161	58
ChemShuttle, Inc.	0510-83588313-811 18800520310;	China	2999	62
Bide Pharmatech Ltd.	400-1647117 13681763483	China	62075	58
TargetMol Chemicals Inc.	4008200310	China	24644	58
RD International Technology Co., Limited	18024082417	China	9266	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	China	7787	56
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	China	11218	58
Taizhou Crene Biotechnology Co. Ltd.	+86-0576-88813233 +86-13396860566	China	1991	58