Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ

136461-80-8

CAS №: 136461-80-8

Химическое название:: Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ

английское имя:: H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH

Синонимы:: Osteocalcin(1-49);BGP (1-49) (HUMAN);BONE GLA PROTEIN (HUMAN);OSTEOCALCIN (1-49) (HUMAN);GLA17,21,24-OSTEOCALCIN (HUMAN);BONE GLA PROTEIN (1-49) (HUMAN);OSTEOCALCIN (HUMAN, GLA17,21,24);[GLA17,21,24]-OSTEOCALCIN (1-49);Osteocalcin fragment 1-49 Human >=94% (HPLC), solid;YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFYGPV

CBNumber:: CB4370884

Формула:: C269H381N67O82S2

молекулярный вес:: 5929.43

MOL File:: 136461-80-8.mol

атрибут

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поставщик 61

продукт поиска:

Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ атрибут

температура хранения:	-20°C
растворимость:	Formic Acid: 1 mg/ml
форма:	Твердый
FDA UNII:	C5F7I87K3N

Заявления о рисках и безопасности

WGK Германия	3
кода HS	2934999090

Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ химические свойства, назначение, производство

Описание

Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget''s disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women. In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans.

Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ препаратная продукция и сырье

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препарат

Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ поставщик

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136461-80-8(Н-Tyr-Leu-Tyr-Gln-ГТО-Leu-Gly-Ala-Pro-Val-PRO-TYR-PRO-Asp-Pro-Leu-ГЛК-Pro-Arg-Arg-ГЛК-Val-Cys-GLA- Leu-Asn-PRO-ASP-Cys-Asp-Glu-НОУ-АЛК-Asp-His-Ile-Gly-Phe-Gln-Glu-АЛК-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val- ОЙ)подобный поиск:

Трис (2,2,6,6-тетраметил-3 ,5-heptanedionato) диспрозий (III) Метил isocyanoacetate Этил изоцианоацета N-бутил изоцианид 1,1,3,3-Тетраметилбутилизоцианид Тозилметил изоцианид Фенилселенол Трис (2,2,6,6-тетраметил-3 ,5-heptanedionato) европий (III) Бензил изоцианид трет-Бутилизоцианид Алюминия ацетилацетона