ANTI-BCL-2 (AB-2) MOUSE MAB
ANTI-BCL-2 (AB-2) MOUSE MAB атрибут
| температура хранения: |
-20°C |
| форма: |
буферный водный раствор |
ANTI-BCL-2 (AB-2) MOUSE MAB химические свойства, назначение, производство
Использование
Monoclonal Anti-Bcl-2 antibody produced in mouse is suitable for western blotting at a concentration of 1:1,000 by using human HeLa cell extract. It is also suitable for immunohistochemistry by using formalin-fixed, paraffin-embedded tissue sections or frozen sections. Further, the antibody may be used for the localization of Bcl-2, by implementing numerous assays like- microarray, electron microscopy and immunoprecipitation.
Общее описание
BCL2 (B-cell lymphoma 2) consists of pro- and antiapoptotic functions. It belongs to BCL2 family of proteins. It is mapped to human chromosome 18q21.3.
Биохимия/физиол Действия
Protooncogene BCL2 encodes a 26 kD integral outer mitochondrial membrane protein expressed in sub-cellular components such as the mitochondria and nucleus. While mitochondrial BCL2 inhibits apoptosis, BCL2 present in the nucleus may activate cell death. It may also regulate autophagy during starvation. Additionally, BCL2 facilitates the survival of central and peripheral neurons grown in culture in the absence of neurotrophic factors.
ANTI-BCL-2 (AB-2) MOUSE MAB препаратная продукция и сырье
сырьё
препарат
ANTI-BCL-2 (AB-2) MOUSE MAB поставщик
Global( 27)Suppliers