(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

1660143-42-9

CAS №: 1660143-42-9

английское имя:: (S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Синонимы:: PR-059462;Kyprolis Impurity Y;Carfilzomib Impurity Y;Alkene Leucine Carfilzomib;L-Phenylalaninamide, (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-buten-1-yl]-;(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide;(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-buten-1-yl]-L-phenylalaninamide(Carfilzomib impurity)

CBNumber:: CB44809164

Формула:: C40H57N5O6

молекулярный вес:: 703.91

MOL File:: 1660143-42-9.mol

атрибут

безопасность

использование

поставщик 21

продукт поиска:

(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide атрибут

Температура кипения:	959.7±65.0 °C(Predicted)
плотность:	1.119±0.06 g/cm3(Predicted)
пка:	13.14±0.46(Predicted)

Заявления о рисках и безопасности

(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide химические свойства, назначение, производство

Использование

(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-buten-1-yl]-L-phenylalaninamide is an impurity/intermediate in the preparation of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide препаратная продукция и сырье

сырьё

препарат

(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide поставщик

Global( 21)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58
Nanjing Vcare PharmaTech Co., Ltd	025-58741518 17366379912	China	490	58
Cato Research Chemicals Inc.	13342851930	China	7591	58
Abydos Scientific	025-84767922 18936879710	China	1005	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	China	1081	58
Shanghai Haohong Scientific Co., Ltd.	400-400-8210725	China	39953	58
Cato Research Chemicals Inc.	020-81960175-877 18933936954	China	7733	58
Nantong Hanfang Biotechnology Co. , Ltd.	18616537568	China	30968	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	China	2578	58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd	18502726233; 18502726233	China	9809	58