(+)-BORNEOL химические свойства, назначение, производство
Химические свойства
Almost insoluble in water, poorly soluble in Propylene glycol, very soluble in alcohol, miscible with most perfume oils. Dry-camphoraceous, woody-peppery odor. The dryness is characteristic and constitutes the main difference from the odor of isoBorneol. The odor of Borneol is often compared to that of a good grade Rosemary oil (in which Borneol is present).
Использование
(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).
Общее описание
(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.
разработк И противоопухолевых препаратов
Wild asparagus root is known as “tian men dong” in traditional Chinese medicine. Itis used to relieve asthma, suppress coughing, and promote expectoration (Huang1998). It is held to be sweet and bitter in flavour and cold in nature, nourishing thelungs and moistening dryness (McNamara and Song 1995). Though studies conductedon asparagus root to examine its biological effects have only been conductedon animals, the evidence so far shows anticancer activity against leukaemia and lungcancer by means of the inhibition of tumour necrosis factor alpha (Huang et al. 2008).
Методы очистки
It can be steam distilled, the distillate is extracted into Et2O, the extract dried with Drierite and evaporated. The residue is then recrystallised from boiling EtOH (charcoal) or pet ether. [Clark & Read J Chem Soc 1773 1934, Beilstein 6 III 295, 6 IV 281.]
(+)-BORNEOL препаратная продукция и сырье
сырьё
препарат