Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 химические свойства, назначение, производство
Использование
Anti-SIRT4 has been used in immunohistochemistry.
Общее описание
SIRT4 (sirtuin 4) belongs to sirtuin family of nicotinamide adenine dinucleotide-dependent enzymes. It is a NAD+-dependent ADP ribosyltransferase, that is located in the mitochondria. SIRT4 protein level is found to be more in ESCC (esophageal squamous cell carcinoma) tissues.
Биохимия/физиол Действия
SIRT4 (sirtuin 4) may involve in the development of esophageal cancer. Growth of HeLa cells can be suppressed by the overexpression of SIRT4. It modulates glutamine metabolism and may also act as a tumor suppressor. It plays some important roles in multiple cellular processes like stress response and longevity. It may act as an important therapeutic target in colorectal cancer.
Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 препаратная продукция и сырье
сырьё
препарат