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N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

 структура
179552-74-0
CAS №
179552-74-0
английское имя:
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
Синонимы:
Afatinib Impurity 137;Dacomitinib Intermediate 2;N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine;N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinam...;N - (3-Chloro-4-fluorophenyl) -7-methoxy-6-nitroquinoline-4-amine;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-;(3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine
CBNumber:
CB52629972
Формула:
C15H10ClFN4O3
молекулярный вес:
348.72
MOL File:
179552-74-0.mol

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine атрибут

Температура кипения: 515.5±50.0 °C(Predicted)
плотность: 1.529±0.06 g/cm3(Predicted)
температура хранения: Keep in dark place,Inert atmosphere,Room temperature
пка: 5.07±0.70(Predicted)

Заявления о рисках и безопасности

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine химические свойства, назначение, производство

Использование

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine препаратная продукция и сырье

сырьё

препарат


N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine поставщик

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