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Aprepitant Impurity 9

 структура
219821-37-1
CAS №
219821-37-1
английское имя:
Aprepitant Impurity 9
Синонимы:
Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber:
CB53358992
Формула:
C24H25F7N4O4
молекулярный вес:
566.47
MOL File:
219821-37-1.mol

Aprepitant Impurity 9 атрибут

плотность: 1.43±0.1 g/cm3(Predicted)
растворимость: soluble in Chloroform, Dichloromethane, Methanol
форма: Solid
пка: 7.86±0.43(Predicted)
цвет: Pale-Yellow
FDA UNII: TQ265G4AMC

Заявления о рисках и безопасности

Aprepitant Impurity 9 химические свойства, назначение, производство

Использование

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 препаратная продукция и сырье

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