АЛЛОПРЕГНАН-3ALPHA-OL-20-ONE химические свойства, назначение, производство
Описание
Allopregnanolone is an endogenous inhibitory pregnane neurosteroid that is synthesized from progesterone . It acts as a positive allosteric modulator of GABAA receptors at nM concentrations (exhibiting the greatest potentiation at isoforms containing δ subunits) and of GABAC receptors at μM concentrations. Allopregnanolone displays effects similar to other GABAA receptor potentiators such as benzodiazepines, including potent anticonvulsant, anxiolytic, and sedative activity.
Использование
(3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain.
Биологическая активность
GABA A receptor positive allosteric modulator. Neuroactive steroid.
АЛЛОПРЕГНАН-3ALPHA-OL-20-ONE препаратная продукция и сырье
сырьё
препарат