ERYTHROMYCIN LACTOBIONATE (200 MG)
ERYTHROMYCIN LACTOBIONATE (200 MG) атрибут
| Температура плавления: |
145-150° |
| плотность: |
0.9083 (rough estimate) |
| показатель преломления: |
1.5300 (estimate) |
| температура хранения: |
Refrigerator |
| растворимость: |
Растворим в воде, легко растворим в безводном этаноле и метаноле, очень мало растворим в ацетоне и хлористом метилене. |
| форма: |
Твердый |
| цвет: |
От белого до не совсем белого |
| Растворимость в воде: |
> 20 г/л (21 °C) |
| FDA UNII: |
33H58I7GLQ |
Заявления о рисках и безопасности
ERYTHROMYCIN LACTOBIONATE (200 MG) химические свойства, назначение, производство
Описание
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.
Химические свойства
White or slightly yellow hygroscopic, powder.
Использование
Macrolide antibacterial.
Общее описание
Erythromycin lactobionate is a water-soluble salt preparedby reacting erythromycin base with lactobiono-σ-lactone. Itoccurs as an amorphous powder that is freely soluble inwater and alcohol and slightly soluble in ether. It is intended,after reconstitution in sterile water, for intravenousadministration to achieve high plasma levels in the treatmentof serious infections.
ERYTHROMYCIN LACTOBIONATE (200 MG) препаратная продукция и сырье
сырьё
препарат
ERYTHROMYCIN LACTOBIONATE (200 MG) поставщик
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