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Гуанадрел

Гуанадрел структура
40580-59-4
CAS №
40580-59-4
Химическое название:
Гуанадрел
английское имя:
Guanadrel
Синонимы:
C07035;Guanadrel;Guanadrel USP/EP/BP;N-(1,4-Dioxaspiro[4.5]dec-2-ylmethyl)guanidine;1-(1,4-Dioxaspiro[4.5]decan-2-ylmethyl)guanidine;2-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)guanidine;Guanidine, N-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)-;2-((1,4-dioxaspiro[4.5]decan-2-yl)methyl)guanidine
CBNumber:
CB5875306
Формула:
C10H19N3O2
молекулярный вес:
213.28
MOL File:
40580-59-4.mol

Гуанадрел атрибут

Температура кипения: 341.5±40.0 °C(Predicted)
плотность: 1.39±0.1 g/cm3(Predicted)
температура хранения: -20°C
растворимость: ДМФ: 30 мг/мл, ДМСО: 30 мг/мл, Этанол: 30 мг/мл
форма: Твердый
пка: 12.59±0.70(Predicted)
цвет: Colorless to light yellow
FDA UNII: 765C9332T4

Заявления о рисках и безопасности

Гуанадрел химические свойства, назначение, производство

Описание

Guanadrel is an adrenergic neuron blocker used for essential hypertension. Its mechanism of action and side effects are similar to those of guanethidine.

Использование

Guanadrel is an adrenergic neuron blocker used for essential hypertension. The mechanism of action and side effects are similar to guanethidine. It is used for treating hypertension in patients who do not respond to thiazide diuretics. It can be used as an adjuvant drug in thiazide treatment for reaching an optimal level of blood pressure.

Определение

ChEBI: A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management f hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).

Гуанадрел препаратная продукция и сырье

сырьё

препарат


Гуанадрел поставщик

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40580-59-4(Гуанадрел)подобный поиск:

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