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ORGOTEIN

 структура
9016-01-7
CAS №
9016-01-7
английское имя:
ORGOTEIN
Синонимы:
Orgoteine;Orgoteina;Einecs 232-771-6;tetracopper,tetrazinc;Orgoteine [inn-french];Orgoteina [inn-spanish];Bovine copper-zinc superoxide dismutase
CBNumber:
CB61230468
Формула:
Cu4Zn4+16
молекулярный вес:
515.744
MOL File:
9016-01-7.mol

ORGOTEIN атрибут

FDA UNII: PKE82W49V1

Заявления о рисках и безопасности

Токсичность LDLo ipr-mus: 60 mg/kg TXAPA9 26,184,73

ORGOTEIN химические свойства, назначение, производство

Описание

Orgotein is the name applied to a group of metalloproteins obtained from various tissuesources, such as hemolyzed plasma-free bovine erythrocytes or beef liver. They are copper – zinc/protein chelates with molecular masses of about 34 000. These compounds have potent superoxide dismutase activity. When administered directly into the joint at 4 mg/week for 6weeks, marked improvement in the mobility of acute rheumatoid patients occurred. Synovial fluid levels of rheumatoid factor and prostaglandin E2 were reduced.

Использование

Anti-inflammatory;antirheumatic.

Всемирная организация здравоохранения(ВОЗ)

Orgotein, bovine superoxide dismutase with anti-inflammatory activity, was introduced in 1968 for the management of rheumatic disorders and for the amelioration of side-effects of radiotherapy. Although not widely registered, it remains available in other countries.

Профиль безопасности

Poison by intravenous and intraperitoneal routes. An experimental teratogen.

ORGOTEIN препаратная продукция и сырье

сырьё

препарат


ORGOTEIN поставщик

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