3'-fluoro-3'-deoxyadenosine
3'-fluoro-3'-deoxyadenosine атрибут
| Температура плавления: |
211-212 °C |
| Температура кипения: |
628.6±65.0 °C(Predicted) |
| плотность: |
2.01±0.1 g/cm3(Predicted) |
| пка: |
12.45±0.70(Predicted) |
| форма: |
Solid |
| цвет: |
White to off-white |
| InChI: |
InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1 |
| ИнЧИКей: |
QCDAWXDDXYQEJJ-QYYRPYCUSA-N |
| SMILES: |
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1F |
Заявления о рисках и безопасности
3'-fluoro-3'-deoxyadenosine химические свойства, назначение, производство
Использование
3'-deoxy-3'-fluoroadenosine can be used as pharmaceutical intermediates for pharmaceutical experimental research.
Биологическая активность
3'-Fluoro-3'-deoxyadenosine was active against a broad range of viruses, encompassing both DNA viruses [pox (vaccinia)], single-stranded (+) RNA viruses [picorna (polio, Coxsackie B), toga (sindbis, Semliki Forest)] and double-stranded RNA viruses (reo). Its antiviral activity spectrum, 3'-fluoro-3'-deoxyadenosine, clearly differed from those adenosine analogs known as inhibitors of S-adenosylhomocysteine hydrolase. 3'-Fluoro-3'-deoxyadenosine also proved effective in vivo in inhibiting tail lesion formation in mice inoculated intravenously with vaccinia virus[1].
3'-fluoro-3'-deoxyadenosine препаратная продукция и сырье
сырьё
препарат
3'-fluoro-3'-deoxyadenosine поставщик
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