НАДФ химические свойства, назначение, производство
Химические свойства
White to slightly yellowish powder
Использование
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions.
β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate is a substrate NADP which plays a role in a variety of metabolic processes.
Биосинтез
A process for preparing NADP sodium salt comprising performing phosphorylation using a polyphosphoric acid or a salt thereof and nicotinamide adenine dinucleotide (NAD+) as substrates in the presence of a polyphosphate-dependent NAD+ kinase from a Mycobacterium, wherein the reaction solution contains 0.1-15% by weight of the polyphosphoric acid or a salt thereof, and 5-150 mM of a divalent metal ion.
Биологические функции
NADP sodium salt is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. It plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes.
Биохимия/физиол Действия
Electron acceptor
Механизм действия
NADP sodium salt exerts its effect by competitively inhibiting nucleotide metabolism through the suppression of enzymes like nucleoside diphosphate kinase (NDPK) and adenosine kinase (ADK). Additionally, it serves as a substrate for enzymes like DNA polymerases and RNA polymerases, enabling the integration of NADP monosodium salt into nucleic acids during replication and transcription.
НАДФ препаратная продукция и сырье
сырьё
препарат