2-этил-1-бутанол химические свойства, назначение, производство
Химические свойства
clear colorless to slightly yellowish liquid
Использование
It is used as a perfuming agent in cosmetics industry. 2-Ethyl-1-butanol is used for the synthesis of various pharmaceutical compounds, such as novel branched Alkyl carbamates, acting as anticonvulsant agent. It is also a solvent used for various organic synthesis, separation processes and ionic liquids, and solvent mixtures for pharmaceutical applications . It is also used to make penetrating oils, corrosion inhibitors, plasticizers, and perfumes; as cleaning agent for printed circuits; and to improve flow of paints and varnishes.
Методы производства
2-Ethylbutanol can be prepared commercially by the aldol
condensation of acetaldehyde and 1-butanal and subsequent
hydrogenation.
Общее описание
Flash point of 137°F. Less dense than water and slightly soluble in water. Vapors are heavier than air. Used as a solvent and in the manufacture of pharmaceuticals.
Реакции воздуха и воды
Flammable. Slightly soluble in water.
Профиль реактивности
Flammable and/or toxic gases are generated by the combination of alcohols, such as 2-ETHYL-1-BUTANOL, with alkali metals, nitrides, and strong reducing agents. Alcohols react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Опасность
Moderate fire risk.
Угроза здоровью
Liquid causes eye burns. Vapors may be mildly irritating to nose and throat.
Пожароопасность
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Профиль безопасности
Moderately toxic by
ingestion and sktn contact. A skin and
severe eye irritant. Flammable liquid when
exposed to heat or flame; can react with
oxidizing materials. To fight fire, use dry
chemical, CO2, foam, fog. When heated to
decomposition it emits acrid smoke and
irritating fumes. See also ALCOHOLS.
Возможный контакт
Used as a solvent; for making dyes,
perfumes, flavorings, and drugs
Метаболизм
Research reported that when 25 mmol (2.55 g) of 2-ethyl-1-butanol was administered by oral gavage to 3.0 kg rabbits (n = 3), 40% of the administered dose was excreted in the urine as the glucuronide within 24 h. Furthermore, Kamil et al. reported that 2-ethyl-1-butanol, 2.55 g (3.1 ml), administered by oral gavage to a rabbit, was excreted in the urine (24 h) as diethylacetylglucuronide. A small amount of methyl-n-propyl ketone was also excreted[1].
Перевозки
UN2275 Ethylbutanol, Hazard Class: 3; Labels:
3-Flammable liquid
Методы очистки
Dry it with CaSO4 for several days, filter and fractionally distil it. [Beilstein 1 IV 1725.]
Несовместимости
May form explosive mixture with air.
Incompatible with oxidizers, strong acids; caustics, isocyanates, amines, isocyanates.
Утилизация отходов
Incineration by spraying or in
paper packaging. Flammable solvent may be added.
2-этил-1-бутанол препаратная продукция и сырье
сырьё
препарат