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ТЕПА

ТЕПА структура
545-55-1
CAS №
545-55-1
Химическое название:
ТЕПА
английское имя:
TEPA
Синонимы:
tef;tapo;TEPA (pesticide);TRIETHYLENEPHOSPHORAMIDE;tri(aziridin-1-yl)phosphine oxide;1,1’,1"-phosphinylidynetris-aziridin;TEPA;a6366;nsc9717;sk-3818
CBNumber:
CB7239584
Формула:
C6H12N3OP
молекулярный вес:
173.16
MOL File:
545-55-1.mol

ТЕПА атрибут

Температура плавления: 41℃
Температура кипения: 299℃
плотность: 1.47
Fp: 135℃
температура хранения: -20°C
растворимость: Chloroform (Sparingly), Methanol (Slightly)
форма: Твердый
пка: 2.74±0.20(Predicted)
Стабильность:: Стабильный.
FDA UNII: GL19M2KE52
МАИР: 3 (Vol. 9, Sup 7) 1987
Система регистрации веществ EPA: Aziridine, 1,1',1''-phosphinylidynetris- (545-55-1)

Заявления о рисках и безопасности

РИДАДР 2811
Класс опасности 6.1(b)
Группа упаковки III
Банк данных об опасных веществах 545-55-1(Hazardous Substances Data)
Токсичность LD50 orally in male rats: 37 mg/kg (Gaines)

ТЕПА химические свойства, назначение, производство

Химические свойства

Colorless crystals. Soluble in water, alcohol, and ether. Combustible.

Использование

Used as insect chemosterilant; in dyeing. Antineoplastic.

Общее описание

An aqueous solution of a colorless crystalline solid. Toxic by skin absorption, ingestion or inhalation. Produces toxic oxides of nitrogen during combustion. Used as a pesticide.

Профиль реактивности

TRIS-(1-AZIRIDINYL) PHOSPHINE OXIDE may react with aqueous solutions of acids or strong bases. Undergoes slow decomposition in water, not considered hazardous. Polymerizes violently at about 255°F. Acid fumes also cause polymerization at ordinary temperatures [USCG, 1999]. May produce highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Угроза здоровью

Inhalation (unlikely unless a heavy mist is formed) causes symptoms similar to those observed after ingestion. Contact with liquid or powder causes irritation of eyes and (on prolonged contact) irritation and burns of skin. Burns are slow to develop and slow to heal. May sensitize on repeated contact. Ingestion causes depression, anorexia, and diarrhea, appearing 2-3 days before death, followed by terminal dyspnea, incoordination, epistaxis, salivation, prostration and cyanosis.

Пожароопасность

Special Hazards of Combustion Products: Phosphoric acid mist may form in fire. Toxic oxides of nitrogen may form.

Профиль безопасности

Poison by ingestion, skin contact, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Human mutation data reported. A corrosive irritant to the skin, eyes, and mucous membranes. When heated to decomposition it emits very toxic fumes of POx and NOx. Used as an acaricide and in the permanentpress treatment of cotton.

ТЕПА препаратная продукция и сырье

сырьё

препарат

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