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N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide

структура
1346572-63-1
CAS №
1346572-63-1
английское имя:
N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide
Синонимы:
GSK03;GSK503;CS-1698;GSK-503;GSK 503;GSK-503;GSK503;GSK 503;GSK-503,EZH2 inhibitor;GSK-503,Inhibitor,inhibit,GSK503,GSK 503,Histone Methyltransferase;N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide;N-[(4,6-Dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide;1H-Indole-4-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-
CBNumber:
CB72738845
Формула:
C31H38N6O2
молекулярный вес:
526.67
MOL File:
1346572-63-1.mol

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide атрибут

Температура кипения: 798.6±60.0 °C(Predicted)
плотность: 1.24±0.1 g/cm3(Predicted)
температура хранения: Store at -20°C
растворимость: ≥21,65 мг/мл в ДМСО; нерастворим в H2O; ≥26,85 мг/мл в этаноле при легком нагревании
форма: Твердый
пка: 11.93±0.10(Predicted)
цвет: White to gray

Заявления о рисках и безопасности

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide химические свойства, назначение, производство

Использование

GSK503 is an EZH2 inhibitor for treating cancer.

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide препаратная продукция и сырье

сырьё

препарат

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide поставщик

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