Аминогуанидин гидрохлорид
Аминогуанидин гидрохлорид атрибут
| Температура плавления: |
162-166 °C(lit.) |
| давление пара: |
0Pa at 25℃ |
| температура хранения: |
Keep in dark place,Sealed in dry,Room Temperature |
| растворимость: |
Полностью растворим в воде |
| форма: |
Кристаллы |
| цвет: |
От белого до не совсем белого |
| Растворимость в воде: |
506,7 г/л при 20℃ |
| Мерк: |
13,440 |
| БРН: |
3909606 |
| LogP: |
-3.55 at 20℃ |
| Справочник по базе данных CAS: |
1937-19-5(CAS DataBase Reference) |
| FDA UNII: |
A2Z7G2RGAH |
| Система регистрации веществ EPA: |
Hydrazinecarboximidamide, monohydrochloride (1937-19-5) |
Аминогуанидин гидрохлорид химические свойства, назначение, производство
Описание
Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 μM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.
Химические свойства
white to off-white crystals
Использование
Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.
Общее описание
Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.
Аминогуанидин гидрохлорид препаратная продукция и сырье
сырьё
препарат
Аминогуанидин гидрохлорид поставщик
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