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2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]-

структура
2653994-08-0
CAS №
2653994-08-0
английское имя:
2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]-
Синонимы:
JDQ-443;Opnurasib;NVP-JDQ443;JDQ443?(NVP-JDQ443);JDQ-443 (Synonyms: NVP-JDQ443);NVP-JDQ443|||JDQ-443|||Opnurasib;2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]-
CBNumber:
CB79709868
Формула:
C29H28ClN7O
молекулярный вес:
526.04
MOL File:
2653994-08-0.mol

2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]- атрибут

Температура кипения: 737.3±60.0 °C(Predicted)
плотность: 1.46±0.1 g/cm3(Predicted)
температура хранения: Store at -20°C
растворимость: ДМСО: 250 мг/мл (475,26 мМ; требуется ультразвук)
пка: 12.55±0.40(Predicted)
форма: Solid
цвет: White to off-white
FDA UNII: Q3W0H3V1LQ

Заявления о рисках и безопасности

2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]- химические свойства, назначение, производство

target

Primary targets: KRAS(G12C)

2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]- препаратная продукция и сырье

сырьё

препарат

2-Propen-1-one, 1-[6-[(4R)-4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro[3.3]hept-2-yl]- поставщик

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