Полигексаметиленгуанидинфосфат
Полигексаметиленгуанидинфосфат атрибут
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Заявления о рисках и безопасности
Полигексаметиленгуанидинфосфат химические свойства, назначение, производство
Использование
Polyhexamethyleneguanidine phosphate (PHMG-P) has been widely used as a disinfectant because of its strong bactericidal activity and low toxicity.
Оценка токсичности
Administration of PHMG-P induced proinflammatory cytokines elevation and infiltration of immune cells into the lungs. Histopathological analysis revealed a dose-dependent exacerbation of both inflammation and pulmonary fibrosis on day 14. PHMG-P also decreased the total cell number and the CD4+/CD8+ cell ratio in the thymus, with the histopathological examination indicating severe reduction of cortex and medulla. The mRNA levels of biomarkers associated with T cell development also decreased markedly. These findings suggest that exposure of lung tissue to PHMG-P leads to pulmonary inflammation and fibrosis as well as thymic atrophy.
Полигексаметиленгуанидинфосфат препаратная продукция и сырье
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препарат
Полигексаметиленгуанидинфосфат поставщик
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89697-78-9(Полигексаметиленгуанидинфосфат)подобный поиск: