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АКОНИТАЗА

АКОНИТАЗА структура
9024-25-3
CAS №
9024-25-3
Химическое название:
АКОНИТАЗА
английское имя:
ACONITASE
Синонимы:
ACO1;ACONITASE;EC 4.2.1.3;ACONITATE HYDRATASE;citrate hydro-lyase;Native Porcine Aconitase;ACONITASE, FROM PIG HEART;Ferritin repressor protein;Human ACO1 Protein, His Tag;aconitase from porcine heart
CBNumber:
CB8153364
Формула:
молекулярный вес:
0
MOL File:
Mol file

АКОНИТАЗА атрибут

температура хранения: -20°C

Заявления о рисках и безопасности

Заявления о безопасности 22-24/25
WGK Германия 3
Токсичность Aconitase is the enzyme that reversibly interconverts citric acid, cis-aconitic acid, and isocitric acid in the tricarboxylic acid cycle (TCA) (formerly known as the citric acid or Krebs cycle) by dehydration and hydration reactions. Aconitase is the target for fluoroacetate, a potent rodenticide, that condenses with oxaloacetate to yield an aconitase inhibitor (fluorocitric acid), with resultant accumulation of citric acid and thus blockage of the TCA cycle, leading to an inhibition of aerobic energy production.

АКОНИТАЗА химические свойства, назначение, производство

Использование

Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases .

Биохимия/физиол Действия

Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity.

АКОНИТАЗА препаратная продукция и сырье

сырьё

препарат


АКОНИТАЗА поставщик

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