(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid атрибут
| Температура кипения: |
607.0±55.0 °C(Predicted) |
| плотность: |
1.469 |
| температура хранения: |
Store at -20°C |
| растворимость: |
ДМСО: нерастворимый; |
| пка: |
6.41±0.50(Predicted) |
| Растворимость в воде: |
Вода: нерастворимая |
| FDA UNII: |
BFE2NBZ7NX |
| Код УВД: |
S01AE08 |
Заявления о рисках и безопасности
(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid химические свойства, назначение, производство
Химические свойства
Yellow to slightly yellow crystalline powder
Фармацевтические приложения
An amino-azepinyl quinolone formulated as a suspension for ophthalmic usage. It exhibits good antistaphylococcal activity, as well as activity against Str. pneumoniae, Enterobacteriaceae, H. influenzae and Mor. catarrhalis. It is weakly active against Corynebacterium spp. and has no useful activity against Ps. aeruginosa. After instillation into the eye, less than 0.1% of the drug reaches the plasma. It is used for bacterial conjunctivitis.
(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid препаратная продукция и сырье
сырьё
препарат
(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid поставщик
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