N-azidoacetylmannosamine-tetraacylated
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361154-30-5
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- CAS №
- 361154-30-5
- английское имя:
- N-azidoacetylmannosamine-tetraacylated
- Синонимы:
- N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz);ManNAz tetraacetate;Ac4ManNAz (80% α isomer);N-Azidoacetylmannosamine-tetraacylated;N-Azidoacetylmannosamine-tetraacylated 95%;1,3,4,6-Tetra-O-acetyl-N-azidoacetylmannosamine;Ac4ManNAz,N-Azidoacetylmannosamine-tetraacylated;1,3,4,6-Tetra-O-acetyl-N-azidoacetyl-D-mannosamine;1,3,4,6-Tetra-O-acetyl-N-azidoacetylmannosamine(Ac4ManNAz);2-[(Azidoacetyl)amino]-2-deoxy-D-mannopyranose 1,3,4,6-tetraacetate
- CBNumber:
- CB83364125
- Формула:
- C16H22N4O10
- молекулярный вес:
- 430.37
- MOL File:
- 361154-30-5.mol
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N-azidoacetylmannosamine-tetraacylated атрибут
| температура хранения: |
-20°C |
| растворимость: |
ДМСО: 100 мг/мл (232,36 мМ; требуется ультразвуковой |
| форма: |
порошок или кристаллы |
| цвет: |
White to light yellow |
Заявления о рисках и безопасности
N-azidoacetylmannosamine-tetraacylated химические свойства, назначение, производство
Описание
N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz) is an unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.
прикладной
N-Azidoacetylmannosamine-tetraacylated (Ac4ManNAz) is an azide-containing metabolic glycoprotein labeling reagent that can be incorporated into the sialic acid biosynthesis pathway. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.
Использование
Tetraacylated N-azidoacetylmannosamine is generally used in click chemistry applications in bioconjugate chemistry.
N-azidoacetylmannosamine-tetraacylated препаратная продукция и сырье
сырьё
препарат
N-azidoacetylmannosamine-tetraacylated поставщик
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