Клометацин химические свойства, назначение, производство
Использование
Clometacin is an antalgic drug that binds to human serum albumin (HSA) and inhibits the binding of indomethacin, warfarin, clofibrate and salicylic acid to HSA.
Всемирная организация здравоохранения(ВОЗ)
Clometacin, an analogue of indometacin, was introduced on the
market in 1971. Subsequently several cases of severe - in some cases fatal -
hepatitis were reported, which led in 1987 to the withdrawal of a high-dosage tablet
formulation, while the indications for a lower dosage tablet were restricted and
duration of the treatment was limited. Eventually all tablet formulations were
removed from the market. Clometacin is not widely registered in other countries.
Клометацин препаратная продукция и сырье
сырьё
препарат