ANTI-P53 химические свойства, назначение, производство
Использование
Monoclonal Anti-p53-Biotin antibody produced in mouse has been used for Western Blotting.
Общее описание
p53 is a tumor suppressor gene expressed in a wide variety of tissues. It is a tetrameric nuclear DNA-binding phosphoprotein. The gene encoding it is localized on human chromosome 17p13.1 and mouse chromosome 11.
Биохимия/физиол Действия
Tumor suppressor p53 has the capability to induce cell cycle arrest and has a role in DNA repair, senescence and apoptosis. It binds to Simian vacuolating virus 40 (SV40) T-antigen and human papilloma virus E6 protein. The p53 gene is mutated in various cancers, such as of the breast, ovarian, bladder, colon and lung.
ANTI-P53 препаратная продукция и сырье
сырьё
препарат