6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

1231930-33-8

CAS №: 1231930-33-8

английское имя:: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Синонимы:: 6-Bromo-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole;Abemaciclib Impurity 1;Abemaciclib Impurity 1 D5;Abemaciclib Impurity 1 D12;6-bromo-4-fluoro-2-methyl-1-(1-methylethyl)-;6-Bromo-4-fluoro-1-isopropyl-2-methylbenzimidazole;6-bromo-4-fluoro-2-methyl-1-propan-2-ylbenzimidazole;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzimidazole;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole;5-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

CBNumber:: CB92500134

Формула:: C11H12BrFN2

молекулярный вес:: 271.13

MOL File:: 1231930-33-8.mol

атрибут

безопасность

использование

поставщик 182

продукт поиска:

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole атрибут

Температура кипения:	353.4±22.0 °C(Predicted)
плотность:	1.49
температура хранения:	Sealed in dry,Room Temperature
пка:	3.48±0.10(Predicted)
InChI:	InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3
ИнЧИКей:	SJQZRZLUEGCXFN-UHFFFAOYSA-N
SMILES:	C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1

Заявления о рисках и безопасности

кода HS	2933998090

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole химические свойства, назначение, производство

Использование

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy.

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole препаратная продукция и сырье

сырьё

1H-Benzimidazole, 5-bromo-7-fluoro-2-methyl- Ethanimidamide,N-(1-methylethyl)- Этанимидамид, N-(4-бромо-2,6-дифторфенил)-N'-(1-метилэтил)- 4-бром-2 ,6-дифторанилин N-Isopropylacetamide Ацетон

препарат

1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole поставщик

Global( 182)Suppliers

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Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	China	20294	58
Amadis Chemical Company Limited	571-89925085	China	131980	58
Watson Biotechnology Co.,Ltd	+86-18186686046 +86-18186686046	China	5849	58
Wuhan Fortuna Chemical Co.,Ltd	+8618007136271	China	5883	58
Shanghai Likang New Materials Co., Limited	+86-16631818819 +86-17736933208	China	9311	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	China	5225	58
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58
Nanjing Fred Technology Co., Ltd	+86-25-84696168 +86-15380713688	China	2427	58