(S) -4-N-Boc-2-метилпиперазин
(S) -4-N-Boc-2-метилпиперазин атрибут
| Температура плавления: |
40-45 °C |
| альфа: |
-16 º (c=1 in dioxane) |
| Температура кипения: |
268.7±15.0 °C(Predicted) |
| плотность: |
0.997±0.06 g/cm3(Predicted) |
| температура хранения: |
Keep in dark place,Inert atmosphere,2-8°C |
| пка: |
8.52±0.40(Predicted) |
| форма: |
Кристаллический порошок |
| цвет: |
От белого до желтого |
| оптическая активность: |
[α]/D -16±2°, c = 1 in dioxane |
| Чувствительный: |
Air Sensitive |
| InChI: |
InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1 |
| ИнЧИКей: |
FMLPQHJYUZTHQS-QMMMGPOBSA-N |
| SMILES: |
N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1 |
| Справочник по базе данных CAS: |
147081-29-6(CAS DataBase Reference) |
(S) -4-N-Boc-2-метилпиперазин химические свойства, назначение, производство
Описание
(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.
Химические свойства
colorless to yellow liquid
Использование
Laboratory chemicals, Manufacture of substances.
(S) -4-N-Boc-2-метилпиперазин препаратная продукция и сырье
сырьё
препарат
(S) -4-N-Boc-2-метилпиперазин поставщик
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