Chemical Safety Data Sheet MSDS / SDS

4-Fluorophenylhydrazine hydrochloride

Revision Date:2024-11-23Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 4-Fluorophenylhydrazine hydrochloride
  • CBnumber: CB2746728
  • CAS: 823-85-8
  • EINECS Number: 212-521-2
  • Synonyms: 4-Fluorophenylhydrazine hydrochloride,4-Fluorphenyl hydrazine hydrochloride

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P405 Store locked up.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Hazard statements
H335 May cause respiratory irritation
H319 Causes serious eye irritation
H315 Causes skin irritation
H301 Toxic if swalloed

SECTION 3: Composition/information on ingredients

Substance

  • Product name: 4-Fluorophenylhydrazine hydrochloride
  • Synonyms: 4-Fluorophenylhydrazine hydrochloride,4-Fluorphenyl hydrazine hydrochloride
  • CAS: 823-85-8
  • EC number: 212-521-2
  • MF: C6H8ClFN2
  • MW: 162.59

SECTION 4: First aid measures

Description of first aid measures

General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas, Hydrogen fluoride

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Further information

No data available

NFPA 704

2
0
0
HEALTH 2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE 0 Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment
Eye/face protection

Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body Protection

Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearancelight brown crystalline
  • OdourNo data available
  • Odour ThresholdNo data available
  • pHNo data available
  • Melting point/freezing pointMelting point/range: >= 300 °C - lit.
  • Initial boiling point and boiling rangeNo data available
  • Flash pointNo data available
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressure No data available
  • Vapour density No data available
  • Relative densityNo data available
  • Water solubilityNo data available
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityNo data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

No data available

Incompatible materials

Oxidizing agents

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas, Hydrogen fluoride

Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
absorption
Inhalation: absorption Dermal: absorption
Skin corrosion/irritation
Possible damages: slight irritation
Serious eye damage/eye irritation
Possible damages: slight irritation
Carcinogenicity
Presumed to have carcinogenic potential for humans
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Specific target organ toxicity - single exposure
Acute oral toxicity - Nausea, Vomiting
Acute inhalation toxicity - slight mucosal irritations, Cough, Shortness of breath
Specific target organ toxicity - repeated exposure Aspiration hazard
Additional Information
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Quantitative data on the toxicity of this product are not available. Further toxicological data:
Property that cannot be excluded on the basis of structure- effect considerations: After absorption:
Risk of methaemoglobin formation with headache, cardiac dysrhythmia, drop in blood pressure, dyspnoea and spasms, principal symptom: cyanosis (blue discolouration of the blood)., lack of appetite, Coma
Damage to:
Kidney, Liver, Lungs Further data:
Other dangerous properties can not be excluded.
This substance should be handled with particular care.

SECTION 12: Ecological information

Toxicity

Persistence and degradability

Bioaccumulative potential

Mobility in soil

Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

Other adverse effects

We have no quantitative data concerning the ecological effects of this product. Further information on ecology

Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a

licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

SECTION 14: Transport information

IATA:IATA:

UN number

ADR/RID:IMDG:IATA:ADR/RID:IMDG:IATA:
IATA:
IATA:

Transport hazard class(es)

ADR/RID: 3 IMDG: 3 IATA: 3
ADR/RID: 3 IMDG: 3 IATA: 3
ADR/RID: - IMDG: - IATA: -
ADR/RID: - IMDG: - IATA: -
ADR/RID: - IMDG: - IATA: -
ADR/RID: 1987 IMDG: 1987 IATA: 1987
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
ADR/RID: 2513 IMDG: 2513 IATA: 2513
ADR/RID: 3077 IMDG: 3077 IATA: 3077
ADR/RID: 1661 IMDG: 1661 IATA: 1661
ADR/RID: 1437 IMDG: 1437 IATA: 1437

UN proper shipping name

ADR/RID: ZIRCONIUM HYDRIDE IMDG: ZIRCONIUM HYDRIDE IATA: Zirconium hydride
ADR/RID: NITROANILINES IMDG: NITROANILINES (o-, m-, p-) IATA: Nitroanilines
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (2-Ethynyl-6- methoxynaphthalene) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (2-Ethynyl-6- IATA: Environmentally hazardous substance, solid, n.o.s. methoxynaphthalene)
ADR/RID: BROMOACETYL BROMIDE IMDG: BROMOACETYL BROMIDE IATA: Bromoacetyl bromide
ADR/RID: III IMDG: III IATA: III
ADR/RID: ALCOHOLS, N.O.S. (But-2-yn-1-ol) IMDG: ALCOHOLS, N.O.S. (But-2-yn-1-ol) IATA: Alcohols, n.o.s. (But-2-yn-1-ol)
ADR/RID: - IMDG: - IATA: -
ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods
ADR/RID: II IMDG: II IATA: II
ADR/RID: II IMDG: II IATA: II

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: - IMDG: - IATA: -
ADR/RID: - IMDG: - IATA: -
ADR/RID: no IMDG Marine pollutant: no IATA: no Special precautions for user Further information Not classified as dangerous in the meaning of transport regulations.
ADR/RID: 3 IMDG: 3 IATA: 3
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: 8 IMDG: 8 IATA: 8
(2-Ethynyl-6- ADR/RID: 9 IMDG: 9 IATA: 9
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
ADR/RID: 4.1 IMDG: 4.1 IATA: 4.1

Packaging group

ADR/RID: II IMDG: II IATA: II
ADR/RID: II IMDG: II IATA: II
ADR/RID: III IMDG: III IATA: III
ADR/RID: II IMDG: II IATA: II
No data available
ADR/RID: III IMDG: III IATA: III
ADR/RID: - IMDG: - IATA: -
ADR/RID: - IMDG: - IATA: -
No data available
No data available
No data available

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no Special precautions for user Further information Not classified as dangerous in the meaning of transport regulations.
ADR/RID: no IMDG Marine pollutant: no IATA: no Special precautions for user Further information Not classified as dangerous in the meaning of transport regulations.
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: no IMDG Marine pollutant: no IATA: no
ADR/RID: yes IMDG Marine pollutant: yes IATA: yes methoxynaphthalene) Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids.
ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available
No data available
No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
United States Toxic Substances Control Act (TSCA) Inventory:Not Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Not Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Not Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Not Listed. website: http://ncis.nier.go.kr
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Not Listed. website: https://www.mee.gov.cn/
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

Recommended Products
Phenylhydrazine hydrochloride SDS Triethylamine hydrochloride SDS D-Glucosamine hydrochloride SDS 4-Fluorophenylhydrazine hydrochloride SDS Hydrazine monohydrochloride SDS 2,4-Difluorophenylhydrazine hydrochloride SDS Methoxyamine Hydrochloride SDS 2-Fluorophenylhydrazine hydrochloride SDS HYDRAZINE SDS Phenylhydrazine SDS