N-Bromosuccinimide
Product identifier
- Product name: N-Bromosuccinimide
- CBnumber: CB2234049
- CAS: 128-08-5
- EINECS Number: 204-877-2
- Synonyms: nbs,N-bromosuccinimide
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: N-Bromosuccinimide
- Synonyms: nbs,N-bromosuccinimide
- CAS: 128-08-5
- EC number: 204-877-2
- MF: C4H4BrNO2
- MW: 177.98
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Special hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) Hydrogen bromide gas Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire. Has a fire-promoting effect due to release of oxygen.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 2 | Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium) | |
| SPEC. HAZ. | OX |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
No metal containers.
Tightly closed. Away from combustible materials and sources of ignition and heat. Do not store near combustible materials.
Storage stability
Recommended storage temperature 2 - 8 °C
Light sensitive. Moisture sensitive. Store under inert gas.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
protective clothing
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancelight yellow powder
- Odourcharacteristic
- Odour ThresholdNo data available
- pHNo data available
- Melting point/freezing pointMelting point/range: 175 - 180 °C - dec.
- Initial boiling point and boiling range221.4°C (rough estimate)
- Flash pointNot applicable
- Evaporation rateNo data available
- Flammability (solid, gas)The product is not flammable. - Test N.1: Test method for readily combustible solids
- Upper/lower flammability or explosive limitsNo data available
- Vapour pressure< 1 hPa at 20 °C - OECD Test Guideline 104
- Vapour density No data available
- Relative densityNo data available
- Water solubility14,8 g/l at 20 °C - (decomposition), soluble
- Partition coefficient: n-octanol/waterNo data available
- Autoignition temperature>400 °C - Relative self-ignition temperature for solids
- Decomposition temperature ca.180 °C -
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesThe substance or mixture is classified as oxidizing with the category 3.
Other safety information
No data available
Reactivity
The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Exothermic reaction with:
Violent reactions possible with: Alcohols
Amines Ammonia anilines
Hydrazine hydrate
iron/iron-containing compounds
can decompose violently in contact with: Water
Risk of explosion with:
Nitriles
Conditions to avoid
Exposure to light. Exposure to moisture. no information available
Incompatible materials
iron/iron-containing compoundsMetals
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicitySymptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Dermal
(OECD Test Guideline 439) Remarks: (ECHA)
Result: The product is a skin sensitizer, sub-category 1B. (OECD Test Guideline 429)
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: Positive results were obtained in some in vitro tests. Test Type: in vitro test
Test system: Human lymphocytes
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 487
Result: positive
Toxicity
static test EC50 - Daphnia magna (Water flea) - 0,65 mg/l - 48 h (OECD Test Guideline 202)
(OECD Test Guideline 201)
Persistence and degradability
Biodegradability aerobic - Exposure time 35 d
Result: 98 % - Readily biodegradable. (OECD Test Guideline 301A)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
UN number
ADR/RID: 3084 IMDG: 3084 IATA: 3084
UN proper shipping name
ADR/RID: CORROSIVE SOLID, OXIDIZING, N.O.S. (N-bromosuccinimide) IMDG: CORROSIVE SOLID, OXIDIZING, N.O.S. (N-bromosuccinimide)
IATA: Corrosive solid, oxidizing, n.o.s. (N-bromosuccinimide)
Transport hazard class(es)
ADR/RID: 8 (5.1) IMDG: 8 (5.1) IATA: 8 (5.1)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.