ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

NITROBENZENE-D5

Revision Date:2023-11-29Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: NITROBENZENE-D5
  • CBnumber: CB7360620
  • CAS: 4165-60-0
  • EINECS Number: 224-014-3
  • Synonyms: Nitrobenzene-d5,Nitrobenzene-d5, 99 atom % d, for NMR

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P330 Rinse mouth.
P320 Specific treatment is urgent (see … on this label).
P308+P313 IF exposed or concerned: Get medical advice/attention.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P201 Obtain special instructions before use.
Hazard statements
H412 Harmful to aquatic life with long lasting effects
H411 Toxic to aquatic life with long lasting effects
H401 Toxic to aquatic life
H373 May cause damage to organs through prolonged or repeated exposure
H372 Causes damage to organs through prolonged or repeated exposure
H361 Suspected of damaging fertility or the unborn child
H351 Suspected of causing cancer
H336 May cause drowsiness or dizziness
H335 May cause respiratory irritation
H330 Fatal if inhaled
H319 Causes serious eye irritation
H315 Causes skin irritation
H310 Fatal in contact with skin
H300 Fatal if swallowed
H227 Combustible liquid

SECTION 3: Composition/information on ingredients

Substance

  • Product name: NITROBENZENE-D5
  • Synonyms: Nitrobenzene-d5,Nitrobenzene-d5, 99 atom % d, for NMR
  • CAS: 4165-60-0
  • EC number: 224-014-3
  • MF: C6D5NO2
  • MW: 128.14

SECTION 4: First aid measures

Description of first aid measures

General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable extinguishing media
Do NOT use water jet.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Further information

Use water spray to cool unopened containers.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of

vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.

For personal protection see section 8.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up

Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13). Keep in suitable, closed containers for disposal.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling

Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.

Advice on protection against fire and explosion

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.

Hygiene measures

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Containers which are

opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and

approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearance liquid
  • OdourNo data available
  • Odour ThresholdNo data available
  • pH8.1 (1g/l, H2O, 20℃)
  • Melting point/freezing point6°C
  • Initial boiling point and boiling range 88 °C at 16 hPa - lit.
  • Flash point88 °C
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limits Upper explosion limit: 40 %(V) Lower explosion limit: 1,8 %(V)
  • Vapour pressure No data available
  • Vapour density No data available
  • Relative density1,253 g/cm3 at 25 °C - lit. No data available
  • Water solubility1.9g/l
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

No data available

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
Oral
Acute toxicity estimate Oral - 100,1 mg/kg (Expert judgment)
LC50 Inhalation - Rat - 4 h - 2,8 mg/l Remarks: (RTECS)
Inhalation: absorption Dermal: absorption
LD50 Dermal - Rabbit - 760 mg/kg Remarks: (ECHA)
The value is given in analogy to the following substances: Nitrobenzene
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation Remarks: (ECHA)
The value is given in analogy to the following substances: Nitrobenzene
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation Remarks: (ECHA)
The value is given in analogy to the following substances: Nitrobenzene
Respiratory or skin sensitization
Remarks: (IUCLID)
The value is given in analogy to the following substances: Nitrobenzene Local lymph node assay (LLNA) - Mouse
Result: Does not cause skin sensitization. (OECD Test Guideline 429)
Remarks: The value is given in analogy to the following substances: Nitrobenzene
Germ cell mutagenicity
Test Type: Micronucleus test Species: Mouse
Cell type: Bone marrow
Application Route: Intraperitoneal injection Method: OECD Test Guideline 474
Result: negative
Remarks: The value is given in analogy to the following substances: Nitrobenzene
Test Type: unscheduled DNA synthesis assay Species: Rat
Cell type: Liver cells Application Route: Oral
Method: OECD Test Guideline 486 Result: negative
Remarks: The value is given in analogy to the following substances: Nitrobenzene
Carcinogenicity
No data available
Reproductive toxicity
May damage fertility.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
Causes damage to organs through prolonged or repeated exposure. - Blood
Aspiration hazard
No data available

SECTION 12: Ecological information

Toxicity

Toxicity to fish
flow-through test LC50 - Danio rerio (zebra fish) - 92,2 mg/l - 96 h (OECD Test Guideline 203)

Remarks: The value is given in analogy to the following substances: Nitrobenzene


Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - 35 mg/l - 48 h (OECD Test Guideline 202)

Remarks: The value is given in analogy to the following substances: Nitrobenzene


Toxicity to algae
IC5 - Scenedesmus quadricauda (Green algae) - 33 mg/l Remarks: (Lit.)


IC50 - Chlorella pyrenoidosa - 18 mg/l - 96 h Remarks: (IUCLID)


static test ErC50 - Chlorella pyrenoidosa - 18 mg/l - 96 h (OECD Test Guideline 201)

Remarks: The value is given in analogy to the following substances: Nitrobenzene


Toxicity to bacteria
static test EC20 - activated sludge - 1.000 mg/l - 30 min

(OECD Test Guideline 209)

Remarks: The value is given in analogy to the following substances: Nitrobenzene


Persistence and degradability

Biodegradability Result: 3,3 % - Not readily biodegradable.

(OECD Test Guideline 301C)

Remarks: The value is given in analogy to the following substances: Nitrobenzene


Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

Toxic to aquatic life with long lasting effects. Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

UN number

ADR/RID: 1662 IMDG: 1662

UN proper shipping name

ADR/RID: NITROBENZENE IMDG: NITROBENZENE IATA: Nitrobenzene

Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

Packaging group

ADR/RID: II IMDG: II IATA: II

Environmental hazards

ADR/RID: yes IMDG Marine pollutant: yes IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Vietnam National Chemical Inventory:Not Listed. website: https://chemicaldata.gov.vn/
United States Toxic Substances Control Act (TSCA) Inventory:Not Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Not Listed. website: https://emb.gov.ph/
Korea Existing Chemicals List (KECL):Not Listed. website: http://ncis.nier.go.kr
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Not Listed. website: https://www.mee.gov.cn/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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