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ChemicalBook >> CAS DataBase List >> 11-KETO FLUPROSTENOL

11-KETO FLUPROSTENOL

11-KETO FLUPROSTENOL price.
  • $72 - $565
  • Product name: 11-KETO FLUPROSTENOL
  • CAS: 62145-07-7
  • MF: C23H27F3O6
  • MW: 456.45
  • EINECS:
  • MDL Number:MFCD05863541
  • Synonyms:FLUPROSTENOL PROSTAGLANDIN D2;11-OXO-9ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;Travoprost Impurity 17（11-keto Fluprostenol）;Travoprost Impurity 22;5-Heptenoic acid, 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-3-oxocyclopentyl]-, (5Z)-;11-KETO FLUPROSTENOL
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number6444DD
  • Product description(Z)-7-[(1R,2R,5S)-5-Hydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3-oxocyclopentyl]hept-5-enoicacid
  • Packaging5mg
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16783
  • Product description11-keto Fluprostenol ≥98%
  • Packaging1mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16783
  • Product description11-keto Fluprostenol ≥98%
  • Packaging5mg
  • Price$319
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16783
  • Product description11-keto Fluprostenol ≥98%
  • Packaging10mg
  • Price$565
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6444DD (Z)-7-[(1R,2R,5S)-5-Hydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3-oxocyclopentyl]hept-5-enoicacid 5mg $452 2021-12-16 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 1mg $72 2024-03-01 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 5mg $319 2024-03-01 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 10mg $565 2024-03-01 Buy

Properties

Boiling point :627.3±55.0 °C(Predicted)
Density :1.331±0.06 g/cm3(Predicted)
solubility :PBS (7.2): 29 mg/ml
pka :4.76±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.

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(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Tafluprost

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