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ChemicalBook >> CAS DataBase List >> 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide

2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide

2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide price.
  • $73 - $1170.31
  • Product name: 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
  • CAS: 114289-47-3
  • MF: C23H39NO4
  • MW: 393.56
  • EINECS:
  • MDL Number:MFCD00869662
  • Synonyms:2,2-dimethyl-n-(2,4,6-trimethoxyphenyl)-dodecanamid ;2,2-DIMETHYL-N-(2,4,6-TRIMETHOXYPHENYL)DODECANAMIDE;CI 976;PD 128042;N-(2,4,6-Trimethoxyphenyl)-2,2-dimethyldodecanamide;CI-976 (PD 128042);Dodecanamide, 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-;inhibit,oral,PD128042,PD 128042,CI-976,Diacylglycerol acyltransferase,PD-128042,Acyltransferase,transferase,secretory,LPAT,acyl-CoA:cholesterol acyltransferase,mono- acylglycerol acyltransferase,endocytic membrane trafficking pathway,ACAT,CI976,Diglyceride acyltransferase,Inhibitor
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerAK Scientific
  • Product number8686CA
  • Product description2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
  • Packaging5mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8686CA
  • Product description2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
  • Packaging25mg
  • Price$459
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0156510
  • Product description2,2-DIMETHYL-N-(2,4,6-TRIMETHOXYPHENYL)DODECANAMIDE 95.00%
  • Packaging10MG
  • Price$697.34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0156510
  • Product description2,2-DIMETHYL-N-(2,4,6-TRIMETHOXYPHENYL)DODECANAMIDE 95.00%
  • Packaging50MG
  • Price$1170.31
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6987
  • Product descriptionCI 976
  • Packaging10mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6987
  • Product descriptionCI 976
  • Packaging25mg
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6987
  • Product descriptionCI 976
  • Packaging50mg
  • Price$573
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17235
  • Product descriptionCI 976 ≥95%
  • Packaging5mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17235
  • Product descriptionCI 976 ≥95%
  • Packaging10mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17235
  • Product descriptionCI 976 ≥95%
  • Packaging25mg
  • Price$324
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17235
  • Product descriptionCI 976 ≥95%
  • Packaging50mg
  • Price$575
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC3743
  • Product descriptionCI 976 >98% (HPLC), solid
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2227
  • Product descriptionCI 976 ≥98%(HPLC)
  • Packaging10
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2227
  • Product descriptionCI 976 ≥98%(HPLC)
  • Packaging50
  • Price$764
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC432775
  • Product descriptionCI 976
  • Packaging25mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254974
  • Product descriptionCI 976
  • Packaging10mg
  • Price$423
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8686CA 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide 5mg $179 2021-12-16 Buy
AK Scientific 8686CA 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide 25mg $459 2021-12-16 Buy
American Custom Chemicals Corporation CHM0156510 2,2-DIMETHYL-N-(2,4,6-TRIMETHOXYPHENYL)DODECANAMIDE 95.00% 10MG $697.34 2021-12-16 Buy
American Custom Chemicals Corporation CHM0156510 2,2-DIMETHYL-N-(2,4,6-TRIMETHOXYPHENYL)DODECANAMIDE 95.00% 50MG $1170.31 2021-12-16 Buy
ApexBio Technology B6987 CI 976 10mg $138 2021-12-16 Buy
ApexBio Technology B6987 CI 976 25mg $305 2021-12-16 Buy
ApexBio Technology B6987 CI 976 50mg $573 2021-12-16 Buy
Cayman Chemical 17235 CI 976 ≥95% 5mg $73 2024-03-01 Buy
Cayman Chemical 17235 CI 976 ≥95% 10mg $138 2024-03-01 Buy
Cayman Chemical 17235 CI 976 ≥95% 25mg $324 2024-03-01 Buy
Cayman Chemical 17235 CI 976 ≥95% 50mg $575 2024-03-01 Buy
Sigma-Aldrich C3743 CI 976 >98% (HPLC), solid 5mg $193 2024-03-01 Buy
Tocris 2227 CI 976 ≥98%(HPLC) 10 $184 2021-12-16 Buy
Tocris 2227 CI 976 ≥98%(HPLC) 50 $764 2021-12-16 Buy
TRC C432775 CI 976 25mg $210 2021-12-16 Buy
Usbiological 254974 CI 976 10mg $423 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :solid
color :White to off-white
InChI :InChI=1S/C23H39NO4/c1-7-8-9-10-11-12-13-14-15-23(2,3)22(25)24-21-19(27-5)16-18(26-4)17-20(21)28-6/h16-17H,7-15H2,1-6H3,(H,24,25)
InChIKey :WAFNZAURAWBNDZ-UHFFFAOYSA-N
SMILES :C(NC1=C(OC)C=C(OC)C=C1OC)(=O)C(C)(C)CCCCCCCCCC

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT-1) is a sterol O-acyltransferase that catalyzes the formation of fatty acid-cholesterol esters, an important step in lipoprotein assembly and dietary cholesterol absorption. CI-976 is a potent, selective inhibitor of ACAT-1 (IC50 = 73 nM). It is orally bioavailable and decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits given a diet that induces hypercholesterolemia. CI-976 also diminishes atherosclerotic activity in hypercholesterolemic rabbits.

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