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ChemicalBook >> CAS DataBase List >> O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI

O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI

O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI price.
  • $32 - $1400
  • Product name: O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI
  • CAS: 132489-69-1
  • MF: C15H19N3O7
  • MW: 353.33
  • EINECS:1533716-785-6
  • MDL Number:MFCD00145022
  • Synonyms:(Z)-Pugnac;O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino-Z-N-phenylcarbamate;O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenyl carbamate ,97%;(Z)-O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-phenylcarbamate;(Z)-PUGNAc min. 99%;O-[2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLI;2-(AcetylaMino)-2-deoxy-N-[[(phenylaMino)carbonyl]oxy]-D-gluconiMidic Acid δ-Lactone;(1Z)-2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-gluconimidic acid delta-lactone
28 prices
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  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product numberW0593
  • Product descriptionO-(2-Acetamido-2-deoxy-D-glucopyranosylidene)aminoN-phenylcarbamate
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW0593
  • Product descriptionO-(2-Acetamido-2-deoxy-D-glucopyranosylidene)aminoN-phenylcarbamate
  • Packaging100mg
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number132489691
  • Product description(5R,6R,7S,8R,Z)-6,7-Dihydroxy-8-(hydroxymethyl)-2,3-dioxo-N-((phenylcarbamoyl)oxy)-1,4-oxazocane-5-carbimidicacid
  • Packaging50mg
  • Price$551.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number132489691
  • Product description(5R,6R,7S,8R,Z)-6,7-Dihydroxy-8-(hydroxymethyl)-2,3-dioxo-N-((phenylcarbamoyl)oxy)-1,4-oxazocane-5-carbimidicacid
  • Packaging100mg
  • Price$1019.2
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCRB0000548
  • Product descriptionO-(2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLIDENE)AMINO N-PHENYL CARBAMATE 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCRB0000548
  • Product descriptionO-(2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLIDENE)AMINO N-PHENYL CARBAMATE 95.00%
  • Packaging10MG
  • Price$733.43
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBICL4035
  • Product description(Z)-PUGNAc 99%min
  • Packaging5mg
  • Price$280
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBICL4035
  • Product description(Z)-PUGNAc 99%min
  • Packaging10mg
  • Price$475
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBICL4035
  • Product description(Z)-PUGNAc 99%min
  • Packaging25mg
  • Price$1047
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberEA06838
  • Product description(Z)-PugNAc
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberEA06838
  • Product description(Z)-PugNAc
  • Packaging10mg
  • Price$130
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberEA06838
  • Product description(Z)-PugNAc
  • Packaging25mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberEA06838
  • Product description(Z)-PugNAc
  • Packaging50mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberEA06838
  • Product description(Z)-PugNAc
  • Packaging100mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17151
  • Product description(Z)-PUGNAc ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17151
  • Product description(Z)-PUGNAc ≥95%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific W0593 O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)aminoN-phenylcarbamate 5mg $144 2021-12-16 Buy
AK Scientific W0593 O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)aminoN-phenylcarbamate 100mg $1400 2021-12-16 Buy
Alichem 132489691 (5R,6R,7S,8R,Z)-6,7-Dihydroxy-8-(hydroxymethyl)-2,3-dioxo-N-((phenylcarbamoyl)oxy)-1,4-oxazocane-5-carbimidicacid 50mg $551.25 2021-12-16 Buy
Alichem 132489691 (5R,6R,7S,8R,Z)-6,7-Dihydroxy-8-(hydroxymethyl)-2,3-dioxo-N-((phenylcarbamoyl)oxy)-1,4-oxazocane-5-carbimidicacid 100mg $1019.2 2021-12-16 Buy
American Custom Chemicals Corporation CRB0000548 O-(2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLIDENE)AMINO N-PHENYL CARBAMATE 95.00% 1MG $135.45 2021-12-16 Buy
American Custom Chemicals Corporation CRB0000548 O-(2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSYLIDENE)AMINO N-PHENYL CARBAMATE 95.00% 10MG $733.43 2021-12-16 Buy
Apolloscientific BICL4035 (Z)-PUGNAc 99%min 5mg $280 2021-12-16 Buy
Apolloscientific BICL4035 (Z)-PUGNAc 99%min 10mg $475 2021-12-16 Buy
Apolloscientific BICL4035 (Z)-PUGNAc 99%min 25mg $1047 2021-12-16 Buy
Biosynth Carbosynth EA06838 (Z)-PugNAc 5mg $70 2021-12-16 Buy
Biosynth Carbosynth EA06838 (Z)-PugNAc 10mg $130 2021-12-16 Buy
Biosynth Carbosynth EA06838 (Z)-PugNAc 25mg $300 2021-12-16 Buy
Biosynth Carbosynth EA06838 (Z)-PugNAc 50mg $550 2021-12-16 Buy
Biosynth Carbosynth EA06838 (Z)-PugNAc 100mg $1000 2021-12-16 Buy
Cayman Chemical 17151 (Z)-PUGNAc ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 17151 (Z)-PUGNAc ≥95% 5mg $139 2024-03-01 Buy

Properties

Melting point :172-175°C
Density :1.53
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml)
form :solid
pka :11.85±0.70(Predicted)
color :White
BRN :4274031
Stability :Moisture and Temperature Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Proteins can be modified post-translationally by the addition of O-linked N-acetylglucosamine (O-GlcNAc). Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT) is a β-N-acetylglucosaminidase that removes GlcNAc from O-glycosylated proteins. PUGNAc is a (phenylcarbamoyl)oxime analog of GlcNAc that reversibly inhibits NCOAT (Ki = 40-110 nM). It also less potently inhibits other hexosaminidases and exochitinases. (Z)-PUGNAc is a stereoisomer of PUGNAc that is a more potent inhibitor of NCOAT than the (E) isomer, both in vitro and in cells.

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