1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile
- $32 - $1900
- Product name: 1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile
- CAS: 1449747-00-5
- MF: C21H19N3O2
- MW: 345.39
- EINECS:
- MDL Number:MFCD28100815
- Synonyms:1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile;CYM-5520;1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-;1-[2-(1-benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-6-oxopyridine-3-carbonitrile;Inhibitor,osteoporosis,LPL Receptor,inhibit,allosteric,Lysophospholipid Receptor,CYM5520,CYM-5520,S1PR2
12 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50
- 1mg
- 5mg
- 10mg
- 25mg
- 10
- 1g
- ManufacturerAK Scientific
- Product number2810DC
- Product description1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-6-oxopyridine-3-carbonitrile
- Packaging5mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5098
- Product descriptionCYM5520
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17638
- Product descriptionCYM 5520 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17638
- Product descriptionCYM 5520 ≥95%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17638
- Product descriptionCYM 5520 ≥95%
- Packaging10mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC43032
- Product descriptionCYM-5520 >98%
- Packaging1g
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number92157
- Product descriptionCYM-5520
- Packaging1mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1014
- Product descriptionCYM-5520 ≥98% (HPLC)
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1014
- Product descriptionCYM-5520 ≥98% (HPLC)
- Packaging25mg
- Price$498
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5418
- Product descriptionCYM5520 ≥99%(HPLC)
- Packaging10
- Price$171
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5418
- Product descriptionCYM5520 ≥99%(HPLC)
- Packaging50
- Price$717
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC991495
- Product descriptionCYM-5520
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2810DC | 1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-6-oxopyridine-3-carbonitrile | 5mg | $201 | 2021-12-16 | Buy |
ApexBio Technology | C5098 | CYM5520 | 5mg | $104 | 2021-12-16 | Buy |
Cayman Chemical | 17638 | CYM 5520 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 17638 | CYM 5520 ≥95% | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 17638 | CYM 5520 ≥95% | 10mg | $166 | 2024-03-01 | Buy |
DC Chemicals | DC43032 | CYM-5520 >98% | 1g | $1900 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 92157 | CYM-5520 | 1mg | $350 | 2021-12-16 | Buy |
Sigma-Aldrich | SML1014 | CYM-5520 ≥98% (HPLC) | 5mg | $120 | 2024-03-01 | Buy |
Sigma-Aldrich | SML1014 | CYM-5520 ≥98% (HPLC) | 25mg | $498 | 2024-03-01 | Buy |
Tocris | 5418 | CYM5520 ≥99%(HPLC) | 10 | $171 | 2021-12-16 | Buy |
Tocris | 5418 | CYM5520 ≥99%(HPLC) | 50 | $717 | 2021-12-16 | Buy |
TRC | C991495 | CYM-5520 | 10mg | $140 | 2021-12-16 | Buy |
Properties
Boiling point :580.5±50.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :-2.80±0.70(Predicted)
form :powder
color :white to beige
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :-2.80±0.70(Predicted)
form :powder
color :white to beige
Safety Information
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Description
Sphingosine-1-phosphate (S1P; ) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P2 has been implicated in multiple biological functions, including Rho activation, inhibition of Rac and cell migration, and in “feed forward” autocrine signaling in NF-κB survival signaling of tumor cells. CYM 5520 is a noncompetitive allosteric agonist of S1P2 (EC50 = 0.48 μM) that does not display agonist activity towards S1P1, S1P3, S1P4, or S1P5.Suppliers and manufacturers
TargetMol Chemicals Inc.
Labnetwork lnc.
Nantong HI-FUTURE Biology Co., Ltd.
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Amadis Chemical Company Limited
Guangzhou Isun Pharmaceutical Co., Ltd
Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.