CYM50308
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- $37 - $1700
- Product name: CYM50308
- CAS: 1345858-76-5
- MF: C20H21F2N3O2S
- MW: 405.46
- EINECS:
- MDL Number:MFCD26142027
- Synonyms:CYM50308;(2Z,5Z)-5-[[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-4-thiazolidinone;4-Thiazolidinone, 5-[[1-(2,4-difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-, (2Z,5Z)-;CYM50308,ML248,LPL Receptor,Lysophospholipid Receptor,CYM 50308,selective,S1P4-R,ML-248,receptor,Inhibitor,Potent,CYM-50308,inhibit,ML 248;(2Z,5Z)-5-{[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]me thylene}-2-[(2-methoxyethyl)imino]-3-methyl-1,3-thiazolidin-4-one;ML 248;ML248;ML-248
16 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 50
- 10mg
- 003
- 50mg
- 002
- ManufacturerAK Scientific
- Product number3410DH
- Product descriptionCID49835928
- Packaging10mg
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5681
- Product descriptionCYM50308
- Packaging10mg
- Price$354
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14667
- Product descriptionCYM 50308 ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14667
- Product descriptionCYM 50308 ≥98%
- Packaging5mg
- Price$90
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14667
- Product descriptionCYM 50308 ≥98%
- Packaging10mg
- Price$142
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14667
- Product descriptionCYM 50308 ≥98%
- Packaging50mg
- Price$618
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028985
- Product descriptionCYM50308 >99.0%
- Packaging1mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028985
- Product descriptionCYM50308 >99.0%
- Packaging5mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028985
- Product descriptionCYM50308 >99.0%
- Packaging10mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number012288
- Product descriptionCYM50308
- Packaging002
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number012288
- Product descriptionCYM50308
- Packaging003
- Price$1700
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4678
- Product descriptionCYM50308 ≥98%(HPLC)
- Packaging10
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4678
- Product descriptionCYM50308 ≥98%(HPLC)
- Packaging50
- Price$1008
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC989445
- Product descriptionCYM50308
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC989445
- Product descriptionCYM50308
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255070
- Product descriptionCYM 50308
- Packaging10mg
- Price$502
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3410DH | CID49835928 | 10mg | $266 | 2021-12-16 | Buy |
| ApexBio Technology | B5681 | CYM50308 | 10mg | $354 | 2021-12-16 | Buy |
| Cayman Chemical | 14667 | CYM 50308 ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 14667 | CYM 50308 ≥98% | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 14667 | CYM 50308 ≥98% | 10mg | $142 | 2024-03-01 | Buy |
| Cayman Chemical | 14667 | CYM 50308 ≥98% | 50mg | $618 | 2024-03-01 | Buy |
| ChemScene | CS-0028985 | CYM50308 >99.0% | 1mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-0028985 | CYM50308 >99.0% | 5mg | $330 | 2021-12-16 | Buy |
| ChemScene | CS-0028985 | CYM50308 >99.0% | 10mg | $550 | 2021-12-16 | Buy |
| DC Chemicals | 012288 | CYM50308 | 002 | $850 | 2021-12-16 | Buy |
| DC Chemicals | 012288 | CYM50308 | 003 | $1700 | 2021-12-16 | Buy |
| Tocris | 4678 | CYM50308 ≥98%(HPLC) | 10 | $239 | 2021-12-16 | Buy |
| Tocris | 4678 | CYM50308 ≥98%(HPLC) | 50 | $1008 | 2021-12-16 | Buy |
| TRC | C989445 | CYM50308 | 1mg | $50 | 2021-12-16 | Buy |
| TRC | C989445 | CYM50308 | 5mg | $75 | 2021-12-16 | Buy |
| Usbiological | 255070 | CYM 50308 | 10mg | $502 | 2021-12-16 | Buy |
Properties
Boiling point :504.0±60.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 1 mg/ml
form :A crystalline solid
pka :0.47±0.20(Predicted)
color :Light yellow to yellow
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 1 mg/ml
form :A crystalline solid
pka :0.47±0.20(Predicted)
color :Light yellow to yellow
Safety Information
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Description
Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P4 couples to Gαi, Gαo, and Gα12/13 proteins leading to the stimulation of MAPK/ERK signaling pathways, as well as to PLC and Rho-Cdc42 activation, and is thought to contribute to immune responses. CYM 50308 is a novel agonist of SIP4 (EC50 = 56 nM) that displays 37-fold selectivity against S1P5 (EC50 = 2.1 μM) and no appreciable activity over the S1P1-3 subtypes at concentrations up to 25 μM.Related product price
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