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ChemicalBook >> CAS DataBase List >> 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE price.
  • $6 - $1396.05
  • Product name: 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
  • CAS: 145100-51-2
  • MF: C7H3ClF6N2O4S2
  • MW: 392.68
  • EINECS:629-110-2
  • MDL Number:MFCD00191833
  • Synonyms:Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine;N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE);2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine ,98%;Comins Triflating Reagent;N-(5-Chloro-2-pyridyl)triflimide N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide Comins Triflating Reagent;N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoroMethane)sulfonylMethanesulfonaMide;2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine;N-(5-Chloropyridin-2-yl)triflimide
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  • ManufacturerAHH
  • Product numberMT-19440
  • Product description2-[N,N-Bis(trifluoromethylsulphonyl)amino]-5chloropyridine 98%
  • Packaging50g
  • Price$325
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ98921
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
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  • Price$10
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ98921
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
  • Packaging500g
  • Price$1090
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberL16929
  • Product description2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99%
  • Packaging5g
  • Price$113.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberL16929
  • Product description2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99%
  • Packaging1g
  • Price$37.65
  • Updated2024-03-01
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  • ManufacturerAlichem
  • Product number145100512
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
  • Packaging100g
  • Price$247.2
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number145100512
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
  • Packaging250g
  • Price$614.04
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number145100512
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
  • Packaging500g
  • Price$998.4
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA131286
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA131286
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98%
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  • Product numberA131286
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98%
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  • ManufacturerAmbeed
  • Product numberA131286
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98%
  • Packaging100g
  • Price$70
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA131286
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98%
  • Packaging25g
  • Price$70
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  • ManufacturerAmbeed
  • Product numberA131286
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98%
  • Packaging500g
  • Price$780
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0018167
  • Product description2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 95.00%
  • Packaging5G
  • Price$849.71
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0018167
  • Product description2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 95.00%
  • Packaging25G
  • Price$1396.05
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-19440 2-[N,N-Bis(trifluoromethylsulphonyl)amino]-5chloropyridine 98% 50g $325 2021-12-16 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 1g $10 2021-12-16 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 500g $1090 2021-12-16 Buy
Alfa Aesar L16929 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99% 5g $113.65 2024-03-01 Buy
Alfa Aesar L16929 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99% 1g $37.65 2024-03-01 Buy
Alichem 145100512 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 100g $247.2 2021-12-16 Buy
Alichem 145100512 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 250g $614.04 2021-12-16 Buy
Alichem 145100512 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 500g $998.4 2021-12-16 Buy
Ambeed A131286 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98% 5g $6 2021-12-16 Buy
Ambeed A131286 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98% 1g $6 2021-12-16 Buy
Ambeed A131286 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98% 10g $36 2021-12-16 Buy
Ambeed A131286 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98% 100g $70 2021-12-16 Buy
Ambeed A131286 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98% 25g $70 2021-12-16 Buy
Ambeed A131286 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 98% 500g $780 2021-12-16 Buy
American Custom Chemicals Corporation HCH0018167 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 95.00% 5G $849.71 2021-12-16 Buy
American Custom Chemicals Corporation HCH0018167 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 95.00% 25G $1396.05 2021-12-16 Buy

Properties

Melting point :45-47 °C(lit.)
Boiling point :77-90°C/0.2mmHg
Density :1.892±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Benzene (Slightly)
form :Solid
pka :-7.71±0.10(Predicted)
color :yellow
Water Solubility :Reacts with water.
Sensitive :Moisture Sensitive
BRN :5833971
Stability :Moisture Sensitive, Unstable in DMSO Solution
InChIKey :TUFGVZMNGTYAQD-UHFFFAOYSA-N
CAS DataBase Reference :145100-51-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.

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