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ChemicalBook >> CAS DataBase List >> AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER

AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER

AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER price.
  • $40 - $1350
  • Product name: AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER
  • CAS: 148451-96-1
  • MF: C22H18F6N2O3
  • MW: 472.38
  • EINECS:
  • MDL Number:MFCD00237267
  • Synonyms:N-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROMETHYL)-BENZYL ESTER;L-732,138;AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER;N-acetyl-L-tryptophan 3,5-bis*(trifluoromethyl)be;L732138;N-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROM ETHYL)BENZ;3,5-bis(trifluoromethyl)benzyl N-acetyltryptophan;N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester,L-732,138
Price23 Properties Safety Information Description
23 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10MG
  • 25mg
  • 50
  • 50mg
  • 100mg
  • 250mg
  • 10
  • 1g
  • ManufacturerAK Scientific
  • Product number9242CA
  • Product description3,5-Bis(trifluoromethyl)benzylN-acetyltryptophan
  • Packaging50mg
  • Price$563
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA801868
  • Product description3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98%
  • Packaging1mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA801868
  • Product description3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98%
  • Packaging5mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA801868
  • Product description3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98%
  • Packaging100mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA801868
  • Product description3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98%
  • Packaging250mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA801868
  • Product description3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98%
  • Packaging1g
  • Price$829
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007694
  • Product descriptionN-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER 95.00%
  • Packaging10MG
  • Price$617.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007694
  • Product descriptionN-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER 95.00%
  • Packaging50MG
  • Price$649.95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6478
  • Product descriptionL-732,138
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6478
  • Product descriptionL-732,138
  • Packaging50mg
  • Price$566
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100988
  • Product description[3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate
  • Packaging1mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100988
  • Product description[3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate
  • Packaging2mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100988
  • Product description[3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate
  • Packaging5mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100988
  • Product description[3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100988
  • Product description[3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021036
  • Product descriptionL-732138 99.43%
  • Packaging1mg
  • Price$85
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9242CA 3,5-Bis(trifluoromethyl)benzylN-acetyltryptophan 50mg $563 2021-12-16 Buy
Ambeed A801868 3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98% 1mg $40 2021-12-16 Buy
Ambeed A801868 3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98% 5mg $67 2021-12-16 Buy
Ambeed A801868 3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98% 100mg $148 2021-12-16 Buy
Ambeed A801868 3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98% 250mg $276 2021-12-16 Buy
Ambeed A801868 3,5-Bis(trifluoromethyl)benzylacetyl-L-tryptophanate 98% 1g $829 2021-12-16 Buy
American Custom Chemicals Corporation API0007694 N-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER 95.00% 10MG $617.3 2021-12-16 Buy
American Custom Chemicals Corporation API0007694 N-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER 95.00% 50MG $649.95 2021-12-16 Buy
ApexBio Technology B6478 L-732,138 10mg $140 2021-12-16 Buy
ApexBio Technology B6478 L-732,138 50mg $566 2021-12-16 Buy
Biosynth Carbosynth FB100988 [3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate 1mg $40 2021-12-16 Buy
Biosynth Carbosynth FB100988 [3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate 2mg $64 2021-12-16 Buy
Biosynth Carbosynth FB100988 [3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate 5mg $125 2021-12-16 Buy
Biosynth Carbosynth FB100988 [3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate 10mg $200 2021-12-16 Buy
Biosynth Carbosynth FB100988 [3,5-Bis(Trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-Indol-3-Yl)propanoate 25mg $350 2021-12-16 Buy
ChemScene CS-0021036 L-732138 99.43% 1mg $85 2021-12-16 Buy
Next Last

Properties

Melting point :147-148 °C(lit.)
Boiling point :554.1±50.0 °C(Predicted)
Density :1.396±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble to 100 mM in ethanol and to 100 mM in DMSO
pka :14.63±0.46(Predicted)
form :powder
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

L-732,138 is a selective nonpeptide tachykinin NK-1R (NK1) antagonist with 1000 fold more potency towards the NK-1R receptor over NK-2R (NK2) and NK-3R (NK3) receptors with an IC50= 2.3 nM. In addition, this compound shows a 200 fold selectivity towards human NK-1R receptors compared to rat NK-1R receptors. Studies suggest that L-732,138 reduces H3 induced skin vascular permeability. L-732,138 has been shown to competitively inhibit the binding of [125I]L-703,606 to the NK-1R receptor. Furthermore, it is known that if histidine 265 or histidine 197 are replaced with alanine on NK-1R receptors the affinity of L-732,138 is reduced.

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Suppliers and manufacturers

Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
TargetMol Chemicals Inc.
LEAPCHEM CO., LTD.
Aladdin Scientific 3B Pharmachem (Wuhan) International Co.,Ltd. Chemsky (shanghai) International Co.,Ltd Guangzhou Isun Pharmaceutical Co., Ltd EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd.