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ChemicalBook >> CAS DataBase List >> 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

$8 - $1224
Product name: 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride
CAS: 1628047-87-9
MF: C19H28Cl2N2
MW: 355.35
EINECS:
MDL Number:MFCD28334264
Synonyms:1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride;ABT199 intermediate1;abt199 int 1;1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine dihydrochloride;1-((4'-chloro-5,5-demethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl-2yl]methyl)piperazine dihydrochloride;1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride;Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2);1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrah ydro-[1,1'-biphenyl]-2-yl)methy)piperazine dihydrochloride

Price13 Properties Safety Information Description

13 prices

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Brand

AK Scientific
Alichem
Ambeed
American Custom Chemicals Corporation
Chemenu
Crysdot
Matrix Scientific
TRC

Package

5MG
250mg
1g
2.5g
5g
10g
25g
100g

ManufacturerAK Scientific
Product numberJ11760
Product descriptionVenetoclaxIntermediate
Packaging100g
Price$425
Updated2021-12-16
Buy

ManufacturerAlichem
Product number1628047879
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride
Packaging25g
Price$400
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA163903
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging250mg
Price$8
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA163903
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging1g
Price$13
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA163903
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging5g
Price$33
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA163903
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging25g
Price$99
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA163903
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging100g
Price$339
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberHCH0419415
Product description1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE DIHYDROCHLORIDE SALT 95.00%
Packaging5MG
Price$457.89
Updated2021-12-16
Buy

ManufacturerChemenu
Product numberCM105012
Product description1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazinedihydrochloride 95+%
Packaging100g
Price$405
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD11242994
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 95+%
Packaging10g
Price$94
Updated2021-12-16
Buy

ManufacturerMatrix Scientific
Product number132846
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging250mg
Price$432
Updated2021-12-16
Buy

ManufacturerMatrix Scientific
Product number132846
Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
Packaging1g
Price$1224
Updated2021-12-16
Buy

ManufacturerTRC
Product numberC371385
Product description1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazineDihydrochloride
Packaging2.5g
Price$470
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	J11760	VenetoclaxIntermediate	100g	$425	2021-12-16	Buy
Alichem	1628047879	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride	25g	$400	2021-12-16	Buy
Ambeed	A163903	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	250mg	$8	2021-12-16	Buy
Ambeed	A163903	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	1g	$13	2021-12-16	Buy
Ambeed	A163903	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	5g	$33	2021-12-16	Buy
Ambeed	A163903	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	25g	$99	2021-12-16	Buy
Ambeed	A163903	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	100g	$339	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0419415	1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE DIHYDROCHLORIDE SALT 95.00%	5MG	$457.89	2021-12-16	Buy
Chemenu	CM105012	1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazinedihydrochloride 95+%	100g	$405	2021-12-16	Buy
Crysdot	CD11242994	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 95+%	10g	$94	2021-12-16	Buy
Matrix Scientific	132846	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	250mg	$432	2021-12-16	Buy
Matrix Scientific	132846	1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%	1g	$1224	2021-12-16	Buy
TRC	C371385	1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazineDihydrochloride	2.5g	$470	2021-12-16	Buy

Properties

storage temp. :Inert atmosphere,Room Temperature
CAS DataBase Reference :1628047-87-9

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.

Description

1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine Dihydrochloride is an intermediate used in the preparation of Venetoclax (A112430), which is a potent and selective BCL-2 inhibitor with potent antitumour activity while sparing platelets. Venetoclax is used to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.

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