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ChemicalBook >> CAS DataBase List >> Apalutamide

Apalutamide

Apalutamide price.
  • $44 - $1987
  • Product name: Apalutamide
  • CAS: 956104-40-8
  • MF: C21H15F4N5O2S
  • MW: 477.43
  • EINECS:807-449-9
  • MDL Number:MFCD22380626
  • Synonyms:ARN-509;AR509;AR509 100G;ARV-509;ARN-509;ARN 509; ARN509;4-(7-(4-Cyano-3-(trifluoromethyl)phenyl)-8-hydroxy-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-f;AR509/AR-509;ARN
23 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 1MG
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberY0375
  • Product descriptionBenzamide,4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-
  • Packaging1g
  • Price$1987
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015790
  • Product descriptionARN-509 95.00%
  • Packaging1MG
  • Price$148.05
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015790
  • Product descriptionARN-509 95.00%
  • Packaging5MG
  • Price$500.82
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8364
  • Product descriptionARN-509
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8364
  • Product descriptionARN-509
  • Packaging10mM(in 1mL DMSO)
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8364
  • Product descriptionARN-509
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8364
  • Product descriptionARN-509
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180925
  • Product descriptionARN509 >98%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA64943
  • Product descriptionARN 509
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA64943
  • Product descriptionARN 509
  • Packaging50mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA64943
  • Product descriptionARN 509
  • Packaging100mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA64943
  • Product descriptionARN 509
  • Packaging500mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA64943
  • Product descriptionARN 509
  • Packaging1g
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17132
  • Product descriptionARN-509 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17132
  • Product descriptionARN-509 ≥98%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17132
  • Product descriptionARN-509 ≥98%
  • Packaging10mg
  • Price$321
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0375 Benzamide,4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl- 1g $1987 2021-12-16 Buy
American Custom Chemicals Corporation API0015790 ARN-509 95.00% 1MG $148.05 2021-12-16 Buy
American Custom Chemicals Corporation API0015790 ARN-509 95.00% 5MG $500.82 2021-12-16 Buy
ApexBio Technology A8364 ARN-509 5mg $80 2021-12-16 Buy
ApexBio Technology A8364 ARN-509 10mM(in 1mL DMSO) $105 2021-12-16 Buy
ApexBio Technology A8364 ARN-509 10mg $140 2021-12-16 Buy
ApexBio Technology A8364 ARN-509 50mg $350 2021-12-16 Buy
Biorbyt Ltd orb180925 ARN509 >98% 100mg $510 2021-12-16 Buy
Biosynth Carbosynth FA64943 ARN 509 10mg $95 2021-12-16 Buy
Biosynth Carbosynth FA64943 ARN 509 50mg $160 2021-12-16 Buy
Biosynth Carbosynth FA64943 ARN 509 100mg $280 2021-12-16 Buy
Biosynth Carbosynth FA64943 ARN 509 500mg $550 2021-12-16 Buy
Biosynth Carbosynth FA64943 ARN 509 1g $850 2021-12-16 Buy
Cayman Chemical 17132 ARN-509 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 17132 ARN-509 ≥98% 5mg $193 2024-03-01 Buy
Cayman Chemical 17132 ARN-509 ≥98% 10mg $321 2024-03-01 Buy

Properties

Density :1.59±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥23.85 mg/mL in DMSO; insoluble in H2O; ≥7.33 mg/mL in EtOH
form :solid
pka :13.83±0.46(Predicted)
color :White to off-white
InChI :InChI=1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31)
InChIKey :HJBWBFZLDZWPHF-UHFFFAOYSA-N
SMILES :C(NC)(=O)C1=CC=C(N2C(=S)N(C3=CC(C(F)(F)F)=C(C#N)N=C3)C(=O)C32CCC3)C=C1F

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment. Phase 3.

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