(AS)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE
- $32 - $1138.78
- Product name: (AS)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE
- CAS: 169675-09-6
- MF: C15H16ClFN2O4
- MW: 342.75
- EINECS:
- MDL Number:MFCD06798313
- Synonyms:RO 60-0175 FUMARATE;1H-Indole-1-ethanaMine, 6-chloro-5-fluoro-a-Methyl-, (aS)-, (2E)-2-butenedioate;(AS)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE;(alpha-S)-6-Chloro-5-fluoro-alpha-methyl-(1H)-indole-1-ethaneaminefumarate;(S)-2-(Chloro-5-fluoro-indol-L-yl)-1-methylethylamine fumarate;1H-Indole-1-ethanamine, 6-chloro-5-fluoro-alpha-methyl-, (alphas)-, (2E)-2-butenedioate (1:1);1H-Indole-1-ethanamine, 6-chloro-5-fluoro-alpha-methyl-, (S)-, (E)-2-butenedioate (1:1);(αS)-6-Chloro-5-fluoro-α-methyl-1H-indole-1-ethanaminefumarate
13 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10MG
- 10
- 50MG
- 100mg
- ManufacturerAK Scientific
- Product number3277BB
- Product descriptionRo60-0175fumarate
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3277BB
- Product descriptionRo60-0175fumarate
- Packaging5mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0000200
- Product description(ALPHA S)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE 95.00%
- Packaging10MG
- Price$275.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0000200
- Product description(ALPHA S)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE 95.00%
- Packaging50MG
- Price$1138.78
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6878
- Product descriptionRo60-0175fumarate
- Packaging10mg
- Price$234
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6878
- Product descriptionRo60-0175fumarate
- Packaging50mg
- Price$975
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29520
- Product descriptionRo 60-0175
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29520
- Product descriptionRo 60-0175
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29520
- Product descriptionRo 60-0175
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1854
- Product descriptionRo60-0175fumarate ≥98%(HPLC)
- Packaging10
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1854
- Product descriptionRo60-0175fumarate ≥98%(HPLC)
- Packaging50
- Price$658
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberR639713
- Product descriptionRo60-0175Fumarate
- Packaging100mg
- Price$925
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256488
- Product descriptionRo 60-0175 fumarate
- Packaging10mg
- Price$409
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3277BB | Ro60-0175fumarate | 1mg | $133 | 2021-12-16 | Buy |
AK Scientific | 3277BB | Ro60-0175fumarate | 5mg | $218 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | BRS0000200 | (ALPHA S)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE 95.00% | 10MG | $275.1 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | BRS0000200 | (ALPHA S)-6-CHLORO-5-FLUORO-ALPHA-METHYL-1H-INDOLE-1-ETHANAMINE FUMARATE 95.00% | 50MG | $1138.78 | 2021-12-16 | Buy |
ApexBio Technology | B6878 | Ro60-0175fumarate | 10mg | $234 | 2021-12-16 | Buy |
ApexBio Technology | B6878 | Ro60-0175fumarate | 50mg | $975 | 2021-12-16 | Buy |
Cayman Chemical | 29520 | Ro 60-0175 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 29520 | Ro 60-0175 | 5mg | $86 | 2024-03-01 | Buy |
Cayman Chemical | 29520 | Ro 60-0175 | 10mg | $138 | 2021-12-16 | Buy |
Tocris | 1854 | Ro60-0175fumarate ≥98%(HPLC) | 10 | $159 | 2021-12-16 | Buy |
Tocris | 1854 | Ro60-0175fumarate ≥98%(HPLC) | 50 | $658 | 2021-12-16 | Buy |
TRC | R639713 | Ro60-0175Fumarate | 100mg | $925 | 2021-12-16 | Buy |
Usbiological | 256488 | Ro 60-0175 fumarate | 10mg | $409 | 2021-12-16 | Buy |
Properties
storage temp. :Desiccate at RT
solubility :Soluble to 5 mM in water and to 20 mM in DMSO
form :Powder
color :White to off-white
solubility :Soluble to 5 mM in water and to 20 mM in DMSO
form :Powder
color :White to off-white
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Ro 60-0175 is an agonist of the serotonin (5-HT) receptor subtype 5-HT2 that stimulates increases in intracellular calcium levels in CHO-K1 cells expressing human 5-HT2A, 5-HT2B, and 5-HT2C receptors (EC50s = 447, 0.9, and 32 nM, respectively). It is selective for human 5-HT2A and 5-HT2C (Kis = 32 and 1 nM, respectively) over human 5-HT1A, 5-HT1D, 5-HT6, and 5-HT7, rat 5-HT1B and 5-HT3, and guinea pig 5-HT4 receptors (Kis = ≥1,995 nM), as well as adenosine A1 and A2, histamine H1-3, dopamine D1-5, α1-, α2-, and β1-adrenergic, M1-5 muscarinic, nicotinic, kainate, AMPA, and μ-, δ-, and κ-opioid receptors (IC50s = >1,000 nM), but does bind to β2-adrenergic receptors (IC50 = 251 nM). In vivo, Ro 60-0175 increases plasma levels of corticosterone, oxytocin, and prolactin in rats (ED50s = 2.43, 4.19, and 4.03 mg/kg, respectively), effects that are not inhibited by the 5-HT2C antagonist SB-242084 or the 5-HT2A antagonist MDL 100,907 (volinanserin; ).More related product prices
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