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ChemicalBook >> CAS DataBase List >> 4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE

4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE

4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE price.
  • $17 - $2230
  • Product name: 4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
  • CAS: 170569-86-5
  • MF: C16H11ClF3N3O2S
  • MW: 401.79
  • EINECS:
  • MDL Number:MFCD00941297
  • Synonyms:SC-236;4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE;4-[5-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOL-1-YL]BENZENESULFONAMIDE;SC-58236;Benzenesulfonamide, 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-;SC 236 - SC 58236;SC-236,gastric,PPAR,cancer,ischemia,Liver,inhibit,allodynia,Inhibitor,fibrogenesis,neuroprotection,COX,Cyclooxygenase,Apoptosis,TNF-α,Peroxisome proliferator-activated receptors,fibrosis,SC236
32 prices
Selected condition:
Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 5mg
  • 10mg
  • 1mg
  • 10
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number3717BB
  • Product description4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number170569865
  • Product description4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
  • Packaging1g
  • Price$828.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number170569865
  • Product description4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
  • Packaging5g
  • Price$2185.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA578005
  • Product descriptionSc236 97%
  • Packaging1mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA578005
  • Product descriptionSc236 97%
  • Packaging5mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA578005
  • Product descriptionSc236 97%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA578005
  • Product descriptionSc236 97%
  • Packaging100mg
  • Price$202
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA578005
  • Product descriptionSc236 97%
  • Packaging250mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008437
  • Product descriptionSC-236 95.00%
  • Packaging10MG
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008437
  • Product descriptionSC-236 95.00%
  • Packaging25MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7533
  • Product descriptionSC236
  • Packaging10mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7533
  • Product descriptionSC236
  • Packaging50mg
  • Price$1095
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2108
  • Product descriptionSC236-SC58236 99%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10004219
  • Product descriptionSC-236 ≥98%
  • Packaging1mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10004219
  • Product descriptionSC-236 ≥98%
  • Packaging5mg
  • Price$69
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10004219
  • Product descriptionSC-236 ≥98%
  • Packaging10mg
  • Price$113
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3717BB 4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 5mg $201 2021-12-16 Buy
Alichem 170569865 4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 1g $828.1 2021-12-16 Buy
Alichem 170569865 4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 5g $2185.4 2021-12-16 Buy
Ambeed A578005 Sc236 97% 1mg $17 2021-12-16 Buy
Ambeed A578005 Sc236 97% 5mg $37 2021-12-16 Buy
Ambeed A578005 Sc236 97% 10mg $55 2021-12-16 Buy
Ambeed A578005 Sc236 97% 100mg $202 2021-12-16 Buy
Ambeed A578005 Sc236 97% 250mg $336 2021-12-16 Buy
American Custom Chemicals Corporation API0008437 SC-236 95.00% 10MG $231 2021-12-16 Buy
American Custom Chemicals Corporation API0008437 SC-236 95.00% 25MG $739.2 2021-12-16 Buy
ApexBio Technology B7533 SC236 10mg $266 2021-12-16 Buy
ApexBio Technology B7533 SC236 50mg $1095 2021-12-16 Buy
Axon Medchem Axon2108 SC236-SC58236 99% 10mg $88 2021-12-16 Buy
Cayman Chemical 10004219 SC-236 ≥98% 1mg $25 2024-03-01 Buy
Cayman Chemical 10004219 SC-236 ≥98% 5mg $69 2024-03-01 Buy
Cayman Chemical 10004219 SC-236 ≥98% 10mg $113 2024-03-01 Buy

Properties

Melting point :146-148°C
Boiling point :543.4±60.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
pka :9.66±0.10(Predicted)
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SC-236 is a highly selective and potent inhibitor of Cox-2 (IC50 of 10 nM) which also inhibits Cox-1 (IC50 of 17.8 μM) and has antitumor properties. SC-236 exhibits longer half-life time and reduced gastric toxicity in the fasting rat model. SC-236 has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. SC-236 exhibits a potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases.

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