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ChemicalBook >> CAS DataBase List >> 1-(2,3-DICHLOROBENZOYL)-5-METHOXY-2-METHYL-3-[2-(4-MORPHOLINYL)ETHYL]-1H-INDOLE

1-(2,3-DICHLOROBENZOYL)-5-METHOXY-2-METHYL-3-[2-(4-MORPHOLINYL)ETHYL]-1H-INDOLE

1-(2,3-DICHLOROBENZOYL)-5-METHOXY-2-METHYL-3-[2-(4-MORPHOLINYL)ETHYL]-1H-INDOLE price.
  • $34 - $1288
  • Product name: 1-(2,3-DICHLOROBENZOYL)-5-METHOXY-2-METHYL-3-[2-(4-MORPHOLINYL)ETHYL]-1H-INDOLE
  • CAS: 180002-83-9
  • MF: C23H24Cl2N2O3
  • MW: 447.35
  • EINECS:
  • MDL Number:MFCD08061200
  • Synonyms:GW 405833;(2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]-METHANONE;1-(2,3-DICHLOROBENZOYL)-5-METHOXY-2-METHYL-3-[2-(4-MORPHOLINYL)ETHYL]-1H-INDOLE;1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-(3-(morpholin-4-yl)ethyl)-1H-indole hydrochloride;GW405833 hydrochloride;(2,3-Dichloro-phenyl)-[5-Methoxy-2-Methyl-3-(2-Morpholin-4-yl-ethyl)-indol-1-yl];Methanone,(2,3-dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]-;(2,3-dichlorophenyl)-[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1-indolyl]methanone hydrochloride
Price14 Properties Safety Information Description
14 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • AstaTech
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 1g
  • 0.25/ G
  • 1/ G
  • ManufacturerAK Scientific
  • Product number1050AL
  • Product description(2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-yl-ethyl)-indol-1-yl]-methanone
  • Packaging1g
  • Price$1288
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67425
  • Product descriptionGW-405833
  • Packaging10mg
  • Price$254
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0028281
  • Product description(2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]METHANONE 95.00%
  • Packaging10MG
  • Price$714.32
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number60344
  • Product description(2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]-METHANONE 97%
  • Packaging0.25/ G
  • Price$393
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number60344
  • Product description(2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]-METHANONE 97%
  • Packaging1/ G
  • Price$981
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20219
  • Product descriptionGW 405833 ≥98%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20219
  • Product descriptionGW 405833 ≥98%
  • Packaging5mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20219
  • Product descriptionGW 405833 ≥98%
  • Packaging10mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20219
  • Product descriptionGW 405833 ≥98%
  • Packaging25mg
  • Price$249
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM268072
  • Product description(2,3-Dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone 95%+
  • Packaging1g
  • Price$743
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11228323
  • Product description(2,3-Dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone 97%
  • Packaging1g
  • Price$787
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG1421
  • Product descriptionGW405833 hydrochloride ≥98% (HPLC), solid
  • Packaging5mg
  • Price$129
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG1421
  • Product descriptionGW405833 hydrochloride ≥98% (HPLC), solid
  • Packaging25mg
  • Price$554
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD431690
  • Product description1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indole
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1050AL (2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-yl-ethyl)-indol-1-yl]-methanone 1g $1288 2021-12-16 Buy
Alfa Aesar J67425 GW-405833 10mg $254 2023-06-20 Buy
American Custom Chemicals Corporation API0028281 (2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]METHANONE 95.00% 10MG $714.32 2021-12-16 Buy
AstaTech 60344 (2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]-METHANONE 97% 0.25/ G $393 2021-12-16 Buy
AstaTech 60344 (2,3-DICHLORO-PHENYL)-[5-METHOXY-2-METHYL-3-(2-MORPHOLIN-4-YL-ETHYL)-INDOL-1-YL]-METHANONE 97% 1/ G $981 2021-12-16 Buy
Cayman Chemical 20219 GW 405833 ≥98% 1mg $34 2024-03-01 Buy
Cayman Chemical 20219 GW 405833 ≥98% 5mg $85 2024-03-01 Buy
Cayman Chemical 20219 GW 405833 ≥98% 10mg $117 2024-03-01 Buy
Cayman Chemical 20219 GW 405833 ≥98% 25mg $249 2024-03-01 Buy
Chemenu CM268072 (2,3-Dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone 95%+ 1g $743 2021-12-16 Buy
Crysdot CD11228323 (2,3-Dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone 97% 1g $787 2021-12-16 Buy
Sigma-Aldrich G1421 GW405833 hydrochloride ≥98% (HPLC), solid 5mg $129 2024-03-01 Buy
Sigma-Aldrich G1421 GW405833 hydrochloride ≥98% (HPLC), solid 25mg $554 2024-03-01 Buy
TRC D431690 1-(2,3-Dichlorobenzoyl)-5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indole 10mg $100 2021-12-16 Buy

Properties

Melting point :47-49℃
storage temp. :2-8°C
solubility :Soluble in DMSO at 10-15mg/ml. Also soluble in ethanol at ~5mg/ml.
form :solid
color :tan

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.

Description

It is a potent and selective CB2 receptor partial agonist (EC50 = 0.65 nM; maximum inhibition = 44.6%). Binds with high affinity to both human and rat CB2 receptors and displays ~ 1200-fold selectivity over CB1 (Ki values are 3.92 and 4772 nM for human recombinant CB2 and CB1 receptors respectively). Produces potent antihyperalgesic effects in several rodent models of pain.

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