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ChemicalBook >> CAS DataBase List >> 5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N'-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE HYDROCHLORIDE

5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N'-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE HYDROCHLORIDE

5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N'-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE HYDROCHLORIDE price.
  • $112.2 - $1170.31
  • Product name: 5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N'-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE HYDROCHLORIDE
  • CAS: 184241-44-9
  • MF: C18H20Cl4N4
  • MW: 434.19
  • EINECS:
  • MDL Number:MFCD05662281
  • Synonyms:5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N'-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE HYDROCHLORIDE;5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediaminehydrochloride;NBI27914HCl;NBI 27914 HYDROCHLORIDE;NBI 27914 >=98% (HPLC);NBI 27914 hydrochlor;4,6-Pyrimidinediamine, 5-chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-
7 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 50
  • 10MG
  • 10
  • 50MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008466
  • Product descriptionNBI 27914 95.00%
  • Packaging10MG
  • Price$697.34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008466
  • Product descriptionNBI 27914 95.00%
  • Packaging50MG
  • Price$1170.31
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberN3911
  • Product descriptionNBI 27914 ≥98% (HPLC)
  • Packaging10mg
  • Price$112.2
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberN3911
  • Product descriptionNBI 27914 ≥98% (HPLC)
  • Packaging50mg
  • Price$691
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number1591
  • Product descriptionNBI27914hydrochloride ≥99%(HPLC)
  • Packaging10
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number1591
  • Product descriptionNBI27914hydrochloride ≥99%(HPLC)
  • Packaging50
  • Price$724
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255950
  • Product descriptionNBI 27914 hydrochloride
  • Packaging10mg
  • Price$423
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0008466 NBI 27914 95.00% 10MG $697.34 2021-12-16 Buy
American Custom Chemicals Corporation API0008466 NBI 27914 95.00% 50MG $1170.31 2021-12-16 Buy
Sigma-Aldrich N3911 NBI 27914 ≥98% (HPLC) 10mg $112.2 2024-03-01 Buy
Sigma-Aldrich N3911 NBI 27914 ≥98% (HPLC) 50mg $691 2022-05-15 Buy
Tocris 1591 NBI27914hydrochloride ≥99%(HPLC) 10 $173 2021-12-16 Buy
Tocris 1591 NBI27914hydrochloride ≥99%(HPLC) 50 $724 2021-12-16 Buy
Usbiological 255950 NBI 27914 hydrochloride 10mg $423 2021-12-16 Buy

Properties

Boiling point :483.7±45.0 °C(Predicted)
Density :1.417±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 16 mg/mL at 60 °C, soluble
form :solid
pka :3.58±0.50(Predicted)
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NBI 27914 hydrochloride is a selective CRF-RI (type 1 corticotropin-releasing factor; CR1) inhibitor. CRF-RI belongs to the family of CRF receptors, which are involved in modifying the autonomic, behavioral, and endocrine immune response to stress. Anterior pituitary studies indicate that NBI 27914 inhibits CRF-stimulation of cAMP and ACTH release. We supply the NBI 27914 hydrochloride form.

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