(S)-A-METHYL-A-[[[(4-NITROPHENYL)AMINO]CARBONYL]AMINO]-N-[[1-(2-PYRIDINYL)CYCLOHEXYL]METHYL]-1H-INDOLE-3-PROPANAMIDE
![(S)-A-METHYL-A-[[[(4-NITROPHENYL)AMINO]CARBONYL]AMINO]-N-[[1-(2-PYRIDINYL)CYCLOHEXYL]METHYL]-1H-INDOLE-3-PROPANAMIDE price.](/CAS/GIF/204066-82-0.gif)
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- $32 - $1270.5
- Product name: (S)-A-METHYL-A-[[[(4-NITROPHENYL)AMINO]CARBONYL]AMINO]-N-[[1-(2-PYRIDINYL)CYCLOHEXYL]METHYL]-1H-INDOLE-3-PROPANAMIDE
- CAS: 204066-82-0
- MF: C31H34N6O4
- MW: 554.64
- EINECS:
- MDL Number:MFCD09971100
- Synonyms:(S)-A-METHYL-A-[[[(4-NITROPHENYL)AMINO]CARBONYL]AMINO]-N-[[1-(2-PYRIDINYL)CYCLOHEXYL]METHYL]-1H-INDOLE-3-PROPANAMIDE;PD 168368;(S)-α-Methyl-α-[[[(4-nitrophenyl)amino]carbonyl]amino]-N-[[1-(2-pyridinyl)cyclohexyl]methyl]-1H-indole-3-propanamide;(2S)-3-(1H-INDOL-3-YL)-2-METHYL-2-[(4-NITROPHENYL)CARBAMOYLAMINO]-N-[(1-PYRIDIN-2-YLCYCLOHEXYL)METHYL]PROPANAMIDE;1H-Indole-3-propanamide, α-methyl-α-[[[(4-nitrophenyl)amino]carbonyl]amino]-N-[[1-(2-pyridinyl)cyclohexyl]methyl]-, (αS)-
7 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 50MG
- ManufacturerAK Scientific
- Product number4346CR
- Product descriptionCID9937534
- Packaging10mg
- Price$484
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0000661
- Product descriptionPD 168368 95.00%
- Packaging10MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0000661
- Product descriptionPD 168368 95.00%
- Packaging50MG
- Price$1270.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17920
- Product descriptionPD 168368 ≥95%
- Packaging500μg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17920
- Product descriptionPD 168368 ≥95%
- Packaging1mg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17920
- Product descriptionPD 168368 ≥95%
- Packaging5mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17920
- Product descriptionPD 168368 ≥95%
- Packaging10mg
- Price$347
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4346CR | CID9937534 | 10mg | $484 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000661 | PD 168368 95.00% | 10MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000661 | PD 168368 95.00% | 50MG | $1270.5 | 2021-12-16 | Buy |
| Cayman Chemical | 17920 | PD 168368 ≥95% | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17920 | PD 168368 ≥95% | 1mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 17920 | PD 168368 ≥95% | 5mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 17920 | PD 168368 ≥95% | 10mg | $347 | 2024-03-01 | Buy |
Properties
Boiling point :819.7±65.0 °C(Predicted)
Density :1.300±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMF: 10 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
form :A crystalline solid
pka :11.60±0.46(Predicted)
color :White to off-white
Density :1.300±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMF: 10 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
form :A crystalline solid
pka :11.60±0.46(Predicted)
color :White to off-white
Safety Information
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Description
PD 168368 is a competitive antagonist of neuromedin B (NMB) receptors (Kis = 15-45 nM for rat and human receptors expressed in various cell lines). It blocks the elevation of intracellular calcium and release of inositol phosphate induced by NMB in cells expressing NMB receptors. PD 168368 is selective for NMB receptors over those for related peptide agonists, including bombesin and gastrin-releasing peptide. It is also an agonist of formyl-peptide receptors (FPRs) at higher concentrations (EC50s = 0.57 and 0.24 μM for FPR1 and FPR2, respectively). PD 168368 induces cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells and blocks neovascularization and cancer cell growth in breast cancer xenograft tumors in mice.More related product prices
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