1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE
- $81 - $782
- Product name: 1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE
- CAS: 289726-02-9
- MF: C29H31N3O3
- MW: 469.57
- EINECS:
- MDL Number:MFCD06411603
- Synonyms:METHYL-PIPERIDINO-PYRAZOLE DIHYDROCHLORIDE;1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE;MPP DIHYDROCHLORIDE;MMP DIHYDROCHLORIDE;MPP2HCl;Methyl-piperidino-pyrazole, 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride;Methylpiperidino pyrazole;TXLGPGWHIIHRHH-UHFFFAOYSA-N
7 prices
Selected condition:
Brand
- ApexBio Technology
- Cayman Chemical
- Tocris
- TRC
Package
- 50
- 5mg
- 10mg
- 10
- 50mg
- ManufacturerApexBio Technology
- Product numberC3089
- Product descriptionMethylpiperidinopyrazole
- Packaging10mg
- Price$172
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13863
- Product descriptionMethylpiperidino pyrazole ≥98%
- Packaging5mg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13863
- Product descriptionMethylpiperidino pyrazole ≥98%
- Packaging10mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13863
- Product descriptionMethylpiperidino pyrazole ≥98%
- Packaging50mg
- Price$632
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1991
- Product descriptionMPPdihydrochloride ≥98%(HPLC)
- Packaging10
- Price$186
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1991
- Product descriptionMPPdihydrochloride ≥98%(HPLC)
- Packaging50
- Price$782
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM745835
- Product descriptionMPP
- Packaging10mg
- Price$520
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
ApexBio Technology | C3089 | Methylpiperidinopyrazole | 10mg | $172 | 2021-12-16 | Buy |
Cayman Chemical | 13863 | Methylpiperidino pyrazole ≥98% | 5mg | $81 | 2024-03-01 | Buy |
Cayman Chemical | 13863 | Methylpiperidino pyrazole ≥98% | 10mg | $152 | 2024-03-01 | Buy |
Cayman Chemical | 13863 | Methylpiperidino pyrazole ≥98% | 50mg | $632 | 2024-03-01 | Buy |
Tocris | 1991 | MPPdihydrochloride ≥98%(HPLC) | 10 | $186 | 2021-12-16 | Buy |
Tocris | 1991 | MPPdihydrochloride ≥98%(HPLC) | 50 | $782 | 2021-12-16 | Buy |
TRC | M745835 | MPP | 10mg | $520 | 2021-12-16 | Buy |
Properties
Boiling point :659.2±55.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Desiccate at +4°C
solubility :DMSO: ≥5 mg/mL, soluble
form :solid
pka :8.80±0.15(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Desiccate at +4°C
solubility :DMSO: ≥5 mg/mL, soluble
form :solid
pka :8.80±0.15(Predicted)
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
Estrogen action is mediated through two estrogen receptor (ER) subtypes, ERα and ERβ, which have distinct target tissue distributions and functional activities. Methylpiperidino pyrazole is an ER antagonist that is highly selective for ERα compared to ERβ (Kis = 5.6 nM and 2.3 μM, respectively). It can inhibit ERα transcriptional activation with an IC50 value of 80 nM. It has been used to evaluate the role of ERα in various estrogen-responsive systems, including certain cancers.More related product prices
Related product price
- 289726-02-9
$81-782
Suppliers and manufacturers
TargetMol Chemicals Inc.
3B Pharmachem (Wuhan) International Co.,Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.
EMMX Biotechnology LLC
Shanghai QianYan Bio-technology Co., Ltd
Shanghai Chaolan Chemical Technology Center
BOC Sciences
Nantong Nuotai Biomedical Technology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Suzhou Chenrui Biotechnology Co. LTD