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ChemicalBook >> CAS DataBase List >> MYCOPHENOLIC ACID GLUCURONIDE

MYCOPHENOLIC ACID GLUCURONIDE

MYCOPHENOLIC ACID GLUCURONIDE price.
  • $120 - $1904.02
  • Product name: MYCOPHENOLIC ACID GLUCURONIDE
  • CAS: 31528-44-6
  • MF: C23H28O12
  • MW: 496.46
  • EINECS:
  • MDL Number:MFCD09878308
  • Synonyms:MYCOPHENOLIC ACID GLUCURONIDE;MYCOPHENOLIC ACID B-D-GLUCURONIDE;5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl b-D-Glucopyranosiduronic Acid;Mycophenolic Acid Glucosiduronate;5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl -D-Glucopyranosiduronic Acid;Mycophenolic Acid -D-Glucuronide;Mycophenolic acid-O-beta-D-glucuronide min. 97%;Mycophenolic acid β-D-glucuronide ,98%
13 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 2.5MG
  • 5mg
  • 10mg
  • 25MG
  • ManufacturerAK Scientific
  • Product numberX3523
  • Product descriptionMycophenolicAcidbeta-D-Glucuronide
  • Packaging5mg
  • Price$729
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberGCN0000014
  • Product descriptionMYCOPHENOLIC ACID GLUCURONIDE 95.00%
  • Packaging2.5MG
  • Price$912.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberGCN0000014
  • Product descriptionMYCOPHENOLIC ACID GLUCURONIDE 95.00%
  • Packaging25MG
  • Price$1904.02
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMM06783
  • Product descriptionMycophenolic acid b-D-glucuronide
  • Packaging1mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMM06783
  • Product descriptionMycophenolic acid b-D-glucuronide
  • Packaging2mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMM06783
  • Product descriptionMycophenolic acid b-D-glucuronide
  • Packaging5mg
  • Price$425
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMM06783
  • Product descriptionMycophenolic acid b-D-glucuronide
  • Packaging10mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMM06783
  • Product descriptionMycophenolic acid b-D-glucuronide
  • Packaging25mg
  • Price$1625
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19078
  • Product descriptionMycophenolic Acid β-D-Glucuronide ≥98%
  • Packaging1mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19078
  • Product descriptionMycophenolic Acid β-D-Glucuronide ≥98%
  • Packaging5mg
  • Price$567
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberM831520
  • Product descriptionMycophenolicAcidβ-D-Glucuronide
  • Packaging2.5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number294059
  • Product descriptionMycophenolic acid b-D-glucuronide
  • Packaging1mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberM9580-16D
  • Product descriptionMycophenolic Acid b-D-Glucuronide
  • Packaging2.5mg
  • Price$475
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X3523 MycophenolicAcidbeta-D-Glucuronide 5mg $729 2021-12-16 Buy
American Custom Chemicals Corporation GCN0000014 MYCOPHENOLIC ACID GLUCURONIDE 95.00% 2.5MG $912.45 2021-12-16 Buy
American Custom Chemicals Corporation GCN0000014 MYCOPHENOLIC ACID GLUCURONIDE 95.00% 25MG $1904.02 2021-12-16 Buy
Biosynth Carbosynth MM06783 Mycophenolic acid b-D-glucuronide 1mg $145 2021-12-16 Buy
Biosynth Carbosynth MM06783 Mycophenolic acid b-D-glucuronide 2mg $230 2021-12-16 Buy
Biosynth Carbosynth MM06783 Mycophenolic acid b-D-glucuronide 5mg $425 2021-12-16 Buy
Biosynth Carbosynth MM06783 Mycophenolic acid b-D-glucuronide 10mg $750 2021-12-16 Buy
Biosynth Carbosynth MM06783 Mycophenolic acid b-D-glucuronide 25mg $1625 2021-12-16 Buy
Cayman Chemical 19078 Mycophenolic Acid β-D-Glucuronide ≥98% 1mg $120 2024-03-01 Buy
Cayman Chemical 19078 Mycophenolic Acid β-D-Glucuronide ≥98% 5mg $567 2024-03-01 Buy
TRC M831520 MycophenolicAcidβ-D-Glucuronide 2.5mg $190 2021-12-16 Buy
Usbiological 294059 Mycophenolic acid b-D-glucuronide 1mg $403 2021-12-16 Buy
Usbiological M9580-16D Mycophenolic Acid b-D-Glucuronide 2.5mg $475 2021-12-16 Buy

Properties

Melting point :98-100°C
Boiling point :875.7±65.0 °C(Predicted)
Density :1.502±0.06 g/cm3(Predicted)
Flash point :2℃
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form :Solid
pka :2.76±0.70(Predicted)
color :White to Pale Beige
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P235 Store in a well-ventilated place. Keep cool.

Description

Mycophenolic acid β-D-glucuronide (MPAG) is the primary metabolite of the antibiotic mycophenolic acid, a potent inhibitor of inosine monophosphate dehydrogenase. Inhibition of this enzyme blocks de novo GTP generation as well as RNA and DNA synthesis in lymphocytes, thus preventing lymphocyte proliferation and activation. Mycophenolic acid, typically used in clinical settings as a chemotherapeutic or immunosuppressant agent, is rapidly conjugated on adsorption and circulates mostly in the form of its glucuronide conjugate. At 6 mg/mouse/day, MPAG has been reported to show significant antitumor activity against Ehrlich solid tumors. This glucuronide is typically used as an internal standard for therapeutic drug monitoring analyses of serum or whole blood by HPLC or LC-MS to confirm that patients remain within the drug’s therapeutic range.

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