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ChemicalBook >> CAS DataBase List >> 16,16-DIMETHYL PROSTAGLANDIN E2

16,16-DIMETHYL PROSTAGLANDIN E2

16,16-DIMETHYL PROSTAGLANDIN E2 price.
  • $86 - $861
  • Product name: 16,16-DIMETHYL PROSTAGLANDIN E2
  • CAS: 39746-25-3
  • MF: C22H36O5
  • MW: 380.52
  • EINECS:
  • MDL Number:MFCD00151141
  • Synonyms:16,16-DIMETHYL PROSTAGLANDIN E2;(5z,11-alpha,13e,15r)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1 ;15r)-13e ;16,16-dimethyl-pge2 ;5-heptenoicacid,7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocycl ;opentyl)- ;prosta-5,13-dien-1-oicacid,11,15-dihydroxy-16,16-dimethyl-9-oxo-,(5z,11-alph ;16,16-DimethylprostaglandineE2
10 prices
Selected condition:
Brand
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 2.5mg
  • 1
  • 1mg
  • 5mg
  • 10mg
  • 1mg(solution)
  • 5mg(solution)
  • 10mg(solution)
  • ManufacturerApexBio Technology
  • Product numberB7568
  • Product description16,16-Dimethylprostaglandin E2
  • Packaging1mg(solution)
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7568
  • Product description16,16-Dimethylprostaglandin E2
  • Packaging5mg(solution)
  • Price$455
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7568
  • Product description16,16-Dimethylprostaglandin E2
  • Packaging10mg(solution)
  • Price$861
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14750
  • Product description16,16-dimethyl Prostaglandin E2 ≥98%
  • Packaging1mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14750
  • Product description16,16-dimethyl Prostaglandin E2 ≥98%
  • Packaging5mg
  • Price$399
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14750
  • Product description16,16-dimethyl Prostaglandin E2 ≥98%
  • Packaging10mg
  • Price$755
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD0160
  • Product description16,16-Dimethylprostaglandin E2 methyl acetate solution
  • Packaging1mg
  • Price$348
  • Updated2023-06-20
  • Buy
  • ManufacturerTocris
  • Product number4027
  • Product description16,16-Dimethylprostaglandin E2 ≥98%(HPLC)
  • Packaging1
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP838673
  • Product description16,16-Dimethylprostaglandin E2
  • Packaging2.5mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254345
  • Product description16,16-Dimethyl Prostaglandin E2
  • Packaging1mg
  • Price$375
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7568 16,16-Dimethylprostaglandin E2 1mg(solution) $96 2021-12-16 Buy
ApexBio Technology B7568 16,16-Dimethylprostaglandin E2 5mg(solution) $455 2021-12-16 Buy
ApexBio Technology B7568 16,16-Dimethylprostaglandin E2 10mg(solution) $861 2021-12-16 Buy
Cayman Chemical 14750 16,16-dimethyl Prostaglandin E2 ≥98% 1mg $86 2024-03-01 Buy
Cayman Chemical 14750 16,16-dimethyl Prostaglandin E2 ≥98% 5mg $399 2024-03-01 Buy
Cayman Chemical 14750 16,16-dimethyl Prostaglandin E2 ≥98% 10mg $755 2024-03-01 Buy
Sigma-Aldrich D0160 16,16-Dimethylprostaglandin E2 methyl acetate solution 1mg $348 2023-06-20 Buy
Tocris 4027 16,16-Dimethylprostaglandin E2 ≥98%(HPLC) 1 $125 2021-12-16 Buy
TRC P838673 16,16-Dimethylprostaglandin E2 2.5mg $660 2021-12-16 Buy
Usbiological 254345 16,16-Dimethyl Prostaglandin E2 1mg $375 2021-12-16 Buy

Properties

Flash point :-13℃
storage temp. :-20°C
solubility :Soluble in methyl acetate
form :methyl acetate solution
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

16,16-dimethyl PGE2 is a competitive inhibitor of 15-hydroxy PGDH, but it is not a substrate for the enzyme. Because of its resistance to metabolism by 15-hydroxy PGDH, it has a prolonged half-life in vivo. 16,16-dimethyl PGE2 acts as an agonist on most EP receptor subtypes, and has been used experimentally to induce cervical ripening, uterine contraction, and prevent ulceration of the gastric mucosa in rats and dogs. The Kd for activation of isolated EP2 receptors is about 1 nM. 16,16-dimethyl PGE2 can be used to preserve the self-renewal properties while preventing the differentiation of hematopoietic stem cells during expansion in culture.

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