15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA
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- $64 - $497
- Product name: 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA
- CAS: 41639-71-8
- MF: C23H32O5
- MW: 388.5
- EINECS:
- MDL Number:MFCD05863952
- Synonyms:9ALPHA-11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA;15(R)-17-phenyl trinor Prostaglandin F2α;Bimatoprost Impurity 3;(15R)-Bimatoprost Acid/(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid;Bimatoprost Impurity 6;Bimatoprost Acid 15-Epimer;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-
4 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number1209AH
- Product description15(R)-17-PhenyltrinorprostaglandinF2alpha
- Packaging5mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16814
- Product description15(R)-17-phenyl trinor Prostaglandin F2α ≥98%
- Packaging1mg
- Price$64
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16814
- Product description15(R)-17-phenyl trinor Prostaglandin F2α ≥98%
- Packaging5mg
- Price$280
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16814
- Product description15(R)-17-phenyl trinor Prostaglandin F2α ≥98%
- Packaging10mg
- Price$497
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1209AH | 15(R)-17-PhenyltrinorprostaglandinF2alpha | 5mg | $410 | 2021-12-16 | Buy |
| Cayman Chemical | 16814 | 15(R)-17-phenyl trinor Prostaglandin F2α ≥98% | 1mg | $64 | 2024-03-01 | Buy |
| Cayman Chemical | 16814 | 15(R)-17-phenyl trinor Prostaglandin F2α ≥98% | 5mg | $280 | 2024-03-01 | Buy |
| Cayman Chemical | 16814 | 15(R)-17-phenyl trinor Prostaglandin F2α ≥98% | 10mg | $497 | 2024-03-01 | Buy |
Properties
Boiling point :597.4±50.0 °C(Predicted)
Density :1.219±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
form :Oil
pka :4.76±0.10(Predicted)
color :Colourless
Density :1.219±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
form :Oil
pka :4.76±0.10(Predicted)
color :Colourless
Safety Information
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Description
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide. Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the human cornea to yield the corresponding free acid, with a conversion rate of about 25 μg/cornea/24 hours. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. 15(R)-17-phenyl trinor PGF2α is the 15-epi, or “unnatural” isomer of this active free acid metabolite. It has much diminished FP receptor-mediated activity, which is generally 1.5 to 2 logs less than the 15(S)-isomer. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.Related product price
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